| Literature DB >> 29597834 |
Thi Quynh Do1, Bich Ngan Truong1, Huong Doan Thi Mai1, Thuy Linh Nguyen1, Van Hung Nguyen1, Hai Dang Nguyen1, Tien Dat Nguyen1,2, The Cuong Nguyen3, Trieu Vung Luong4, Loc Thang Giang5, Van Minh Chau1, Van Cuong Pham1.
Abstract
Four new compounds N-salicyl-3-hydroxyanthranilic acid methyl ester (1), N-(2'-dehydroxysalicyl)-3-hydroxyanthranilic acid methyl ester (2), methyl-4-β-D-allopyranosyl-ferulate (3), and methyl-4-β-D-gulopyranosyl-cinnamate (4), along with six known compounds (5-10), were isolated from the roots of Aconitum carmichelii Debx. Their structures were elucidated on the basis of spectral data analysis, including 1D, 2D-NMR, and HR-ESI-MS. Compounds 1 and 2 showed the inhibition of nitric oxide (NO) production with IC50 values of 9.13 and 19.94 μM, respectively.Entities:
Keywords: ; NO production inhibition; Ranunculaceae; cinnamic ester glucoside; dianthramide
Year: 2018 PMID： 29597834 DOI： 10.1080/10286020.2018.1454436
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569