Nam Ju Lee1, Ralph H Hruban2, Elliot K Fishman3. 1. Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, 601 N. Caroline Street, Baltimore, MD, 21287, USA. nlee54@jhmi.edu. 2. Department of Pathology, Johns Hopkins School of Medicine, 600 N. Wolfe Street, Baltimore, MD, 21287, USA. 3. Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, 601 N. Caroline Street, Baltimore, MD, 21287, USA.
Abstract
OBJECTIVE: Pancreatic neuroendocrine tumors (PanNETs) are uncommon pancreatic neoplasms and can be a diagnostic challenge with heterogeneous spectrum of CT appearance. We review CT findings of PanNETs and other mimics. CONCLUSION: PanNETs are typically hypervascular and have avid enhancement on arterial and venous phase images. However, dedicated pancreas protocol may be needed due to their sometimes atypical appearance including transient enhancement. Careful evaluation of CT findings will help differentiate PanNETs from their mimics, and can be used to establish the diagnosis of a PanNETs. Although an accurate diagnosis can be based on serological, urine, and CT scan findings, confirmation is made via pathological examination.
OBJECTIVE:Pancreatic neuroendocrine tumors (PanNETs) are uncommon pancreatic neoplasms and can be a diagnostic challenge with heterogeneous spectrum of CT appearance. We review CT findings of PanNETs and other mimics. CONCLUSION: PanNETs are typically hypervascular and have avid enhancement on arterial and venous phase images. However, dedicated pancreas protocol may be needed due to their sometimes atypical appearance including transient enhancement. Careful evaluation of CT findings will help differentiate PanNETs from their mimics, and can be used to establish the diagnosis of a PanNETs. Although an accurate diagnosis can be based on serological, urine, and CT scan findings, confirmation is made via pathological examination.
Authors: Motoyo Yano; Anup S Shetty; Greg A Williams; Samantha Lancia; Nikolaos A Trikalinos; Chet W Hammill; William G Hawkins; Amber Salter; Deyali Chatterjee Journal: Abdom Radiol (NY) Date: 2022-02-15
Authors: Milica Mitrovic-Jovanovic; Nikica Grubor; Stefan Milosevic; Aleksandra Jankovic; Katarina Stosic; Slavenko Ostojic; Aleksandar Ninic; Marjan Micev; Jelena Djokic Kovac Journal: Diagnostics (Basel) Date: 2022-04-15