Literature DB >> 2959340

Improvement in sensitivity of fast atom bombardment mass spectrometry of amino acids by di-isopropylphosphorylation.

W G Chai1, L Yan, G H Wang, X Y Liang, Y F Zhao, G J Ji.   

Abstract

Positive ion fast atom bombardment mass spectrometric sensitivities of seven amino acids and the corresponding di-isopropylphosphorylated derivatives were carefully compared. Results showed that an improvement in sensitivity by factors of 4-29, mostly above 10, were achieved after the derivatization. The chemical noise derived from glycerol matrix was also greatly reduced by this derivatization.

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Year:  1987        PMID: 2959340     DOI: 10.1002/bms.1200140706

Source DB:  PubMed          Journal:  Biomed Environ Mass Spectrom        ISSN: 0887-6134


  1 in total

1.  A picomole-scale method for rapid peptide sequencing through convenient and efficient N-terminal phosphorylation and electrospray ionization mass spectrometry.

Authors:  Feng Wang; Hua Fu; Yuyang Jiang; Yufen Zhao
Journal:  J Am Soc Mass Spectrom       Date:  2006-06-06       Impact factor: 3.109

  1 in total

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