Literature DB >> 29589640

The role of regulatory T cells and anti-inflammatory cytokines in psoriasis.

Agnieszka Owczarczyk-Saczonek1, Joanna Czerwińska1, Waldemar Placek1.   

Abstract

Psoriasis is a chronic inflammatory disease with a genetic predisposition that can be triggered by environmental factors. Pathogenesis is characterized by activation of the Th1/Th2 axis and abnormalities of the Th17/Treg balance as well as deficiency of anti-inflammatory cytokines (IL-10, TGF-β). Regulatory lymphocytes (Treg), which are involved in homeostasis mechanisms, maintain tolerance and prevent autoimmune disorders. Only a few studies have investigated the presence of Treg marker expression and levels of anti-inflammatory cytokines in psoriatic skin and sera of patients with psoriasis. The results of studies are controversial. This article reviews and analyzes what is known about the role of Treg cells and anti-inflammatory cytokines in psoriasis.

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Year:  2018        PMID： 29589640

Source DB:  PubMed          Journal:  Acta Dermatovenerol Alp Pannonica Adriat        ISSN： 1318-4458


  11 in total

1.  Dysfunction of regulatory T cells mediated by AKT-FOXO1 signaling pathway occurs during the development of psoriasis.

Authors:  Zhixia Fan; Lingyu Li; Xin Wang; Guoying Miao
Journal:  Int J Clin Exp Pathol       Date:  2020-04-01

2.  Total flavonoids from Tetrastigma hemsleyanum ameliorates inflammatory stress in concanavalin A-induced autoimmune hepatitis mice by regulating Treg/Th17 immune homeostasis.

Authors:  Weiwei Ji; Xin Peng; Tianling Lou; Juan Wang; Wenyu Qiu
Journal:  Inflammopharmacology       Date:  2019-05-23       Impact factor: 4.473

3.  Fibrinogen-Like Protein 1 as a Novel Biomarker of Psoriasis Severity.

Authors:  Xiaoying Sun; Liu Liu; Siting Chen; Jiao Wang; Xiaoce Cai; Jiankun Song; Mi Zhou; Dongjie Guo; Le Kuai; Xiaojie Ding; Bin Li; Xin Li
Journal:  J Inflamm Res       Date:  2022-08-15

4.  'Psoriasis 1' reduces T‑lymphocyte‑mediated inflammation in patients with psoriasis by inhibiting vitamin D receptor‑mediated STAT4 inactivation.

Authors:  Yang Gao; Wen Sun; Xushan Cha; Hailong Wang
Journal:  Int J Mol Med       Date:  2020-08-06       Impact factor: 4.101

Review 5.  Current Concepts of Psoriasis Immunopathogenesis.

Authors:  Marijana Vičić; Marija Kaštelan; Ines Brajac; Vlatka Sotošek; Larisa Prpić Massari
Journal:  Int J Mol Sci       Date:  2021-10-26       Impact factor: 5.923

Review 6.  The Role of Exposomes in the Pathophysiology of Autoimmune Diseases II: Pathogens.

Authors:  Aristo Vojdani; Elroy Vojdani; Avi Z Rosenberg; Yehuda Shoenfeld
Journal:  Pathophysiology       Date:  2022-06-03

Review 7.  Homocysteine and psoriasis.

Authors:  Xiran Lin; Xianmin Meng; Zhiqi Song
Journal:  Biosci Rep       Date:  2019-11-29       Impact factor: 3.840

8.  The Effect of Three-Month Vitamin D Supplementation on the Levels of Homocysteine Metabolism Markers and Inflammatory Cytokines in Sera of Psoriatic Patients.

Authors:  Alma Prtina; Nela Rašeta Simović; Tatjana Milivojac; Milorad Vujnić; Milkica Grabež; Dragan Djuric; Miloš P Stojiljković; Valentina Soldat Stanković; Miodrag J Čolić; Ranko Škrbić
Journal:  Biomolecules       Date:  2021-12-11

9.  Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways.

Authors:  Aimin Liu; Buxin Zhang; Wei Zhao; Yuanhui Tu; Qingxing Wang; Jing Li
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

Review 10.  Potential Clinical Applications of the Postbiotic Butyrate in Human Skin Diseases.

Authors:  Serena Coppola; Carmen Avagliano; Antonia Sacchi; Sonia Laneri; Antonio Calignano; Luana Voto; Anna Luzzetti; Roberto Berni Canani
Journal:  Molecules       Date:  2022-03-12       Impact factor: 4.411
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