Literature DB >> 29589151

EACR-MRS conference on Seed and Soil: In Vivo Models of Metastasis.

I Teles Alves1, N Cohen2, P G Ersan3, R Eyre4, I Godet5,6, D Holovanchuk7, R Jackstadt8, L Kyjacova9, K Mahal7, A Noguera-Castells10, L Recalde-Percaz11,10, J P Sleeman8,12,13.   

Abstract

New experimental tools are urgently required to better understand the metastatic process. The importance of such tools is underscored by the fact that many anti-cancer therapies are generally ineffective against established metastases. This makes a major contribution to the fact that metastatic spread is responsible for over 90% of cancer patient deaths. It was therefore timely that the recent "Seed and Soil: In Vivo Models of Metastasis" conference held in Berlin, Germany (27-29 of November 2017) aimed to give an in-depth overview of the latest research models and tools for studying metastasis, and to showcase recent findings from world-leading metastasis researchers. This Meeting Report summarises the major themes of this ground-breaking conference.

Entities:  

Keywords:  Metastasis; Mouse models; Signaling

Mesh:

Year:  2018        PMID: 29589151     DOI: 10.1007/s10585-018-9886-x

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN: 0262-0898            Impact factor:   5.150


  34 in total

1.  Rapid leukocyte migration by integrin-independent flowing and squeezing.

Authors:  Tim Lämmermann; Bernhard L Bader; Susan J Monkley; Tim Worbs; Roland Wedlich-Söldner; Karin Hirsch; Markus Keller; Reinhold Förster; David R Critchley; Reinhard Fässler; Michael Sixt
Journal:  Nature       Date:  2008-05-01       Impact factor: 49.962

Review 2.  Mouse models of advanced spontaneous metastasis for experimental therapeutics.

Authors:  Giulio Francia; William Cruz-Munoz; Shan Man; Ping Xu; Robert S Kerbel
Journal:  Nat Rev Cancer       Date:  2011-02       Impact factor: 60.716

3.  CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis.

Authors:  Bin-Zhi Qian; Jiufeng Li; Hui Zhang; Takanori Kitamura; Jinghang Zhang; Liam R Campion; Elizabeth A Kaiser; Linda A Snyder; Jeffrey W Pollard
Journal:  Nature       Date:  2011-06-08       Impact factor: 49.962

4.  MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.

Authors:  Ulrike Stein; Wolfgang Walther; Franziska Arlt; Holger Schwabe; Janice Smith; Iduna Fichtner; Walter Birchmeier; Peter M Schlag
Journal:  Nat Med       Date:  2008-12-21       Impact factor: 53.440

5.  Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement.

Authors:  Anna Haeger; Marina Krause; Katarina Wolf; Peter Friedl
Journal:  Biochim Biophys Acta       Date:  2014-04-08

Review 6.  Preclinical mouse solid tumour models: status quo, challenges and perspectives.

Authors:  Nicolas Gengenbacher; Mahak Singhal; Hellmut G Augustin
Journal:  Nat Rev Cancer       Date:  2017-10-27       Impact factor: 60.716

7.  Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.

Authors:  U-P Rohr; P Herrmann; K Ilm; H Zhang; S Lohmann; A Reiser; A Muranyi; J Smith; S Burock; M Osterland; K Leith; S Singh; P Brunhoeber; R Bowermaster; J Tie; M Christie; H-L Wong; P Waring; K Shanmugam; P Gibbs; U Stein
Journal:  Ann Oncol       Date:  2017-08-01       Impact factor: 32.976

8.  Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12.

Authors:  B Su; L Gao; F Meng; L-W Guo; J Rothschild; I H Gelman
Journal:  Oncogene       Date:  2012-06-18       Impact factor: 9.867

9.  Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1.

Authors:  N Cohen; O Shani; Y Raz; Y Sharon; D Hoffman; L Abramovitz; N Erez
Journal:  Oncogene       Date:  2017-04-03       Impact factor: 9.867

10.  Incipient Melanoma Brain Metastases Instigate Astrogliosis and Neuroinflammation.

Authors:  Hila Schwartz; Eran Blacher; Malak Amer; Nir Livneh; Lilach Abramovitz; Anat Klein; Dikla Ben-Shushan; Shelly Soffer; Raquel Blazquez; Alonso Barrantes-Freer; Meike Müller; Karin Müller-Decker; Reuven Stein; Galia Tsarfaty; Ronit Satchi-Fainaro; Viktor Umansky; Tobias Pukrop; Neta Erez
Journal:  Cancer Res       Date:  2016-06-03       Impact factor: 12.701

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  1 in total

1.  Real-time ex vivo perfusion of human lymph nodes invaded by cancer (REPLICANT): a feasibility study.

Authors:  Rachel Barrow-McGee; Julia Procter; Julie Owen; Natalie Woodman; Cristina Lombardelli; Ashutosh Kothari; Tibor Kovacs; Michael Douek; Simi George; Peter A Barry; Kelvin Ramsey; Amy Gibson; Richard Buus; Erle Holgersen; Rachael Natrajan; Syed Haider; Michael J Shattock; Cheryl Gillett; Andrew Nj Tutt; Sarah E Pinder; Kalnisha Naidoo
Journal:  J Pathol       Date:  2019-12-22       Impact factor: 7.996

  1 in total

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