Literature DB >> 29588301

Leiomyosarcoma: a rare sinonasal malignancy.

Matthew Ming Kei Kwok1, Stewart Lee1, Patrick Hosking2.   

Abstract

Leiomyosarcomas (LMS) are rare sinonasal malignant tumours with 20 cases of nasal LMS previously reported in the literature. An 81-year-old man presented with an incidental left nasal lesion associated with left nasal obstruction and occasional left-sided blood-stained rhinorrhoea. Nasendoscopic examination showed green coloured polyps filling the left nasal cavity with biopsies showing LMS. CT imaging did not show any bony erosion. No metastases were found on positron emission tomography imaging. The patient underwent endoscopic resection and all surgical margins were clear of disease. The patient was declined postoperative radiotherapy, and serial follow-up has not shown any recurrence to date. Nasal LMS are rare sinonasal smooth muscle tumours and symptoms and radiological findings are often non-specific. Therefore, diagnosis is made on histopathological and immunohistochemical analysis. Due to their invasive nature, the treatment of choice is complete surgical resection, with adjuvant therapy reserved for patients with locally advanced or metastatic disease. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  head and neck cancer; otolaryngology / ent

Mesh:

Year:  2018        PMID: 29588301      PMCID: PMC5878274          DOI: 10.1136/bcr-2017-224110

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  16 in total

Review 1.  Leiomyosarcoma of the nasal cavity. Case report and literature review.

Authors:  B M Lippert; G S Godbersen; J Lüttges; J A Werner
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1996 Mar-Apr       Impact factor: 1.538

2.  Leiomyosarcoma of the maxillary sinus: CT and MRI findings.

Authors:  H Tanaka; P L Westesson; D C Wilbur
Journal:  Br J Radiol       Date:  1998-02       Impact factor: 3.039

3.  Leiomyosarcoma of the sinonasal tract. A clinicopathologic study of nine cases.

Authors:  A Kuruvilla; B M Wenig; D M Humphrey; D K Heffner
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1990-11

Review 4.  Multifocal, recurrent sinonasal leiomyosarcoma: case report and review of literature.

Authors:  Vardan Papoian; Bharat B Yarlagadda; Anand K Devaiah
Journal:  Am J Otolaryngol       Date:  2013-11-07       Impact factor: 1.808

5.  Leiomyosarcoma of the head and neck: a clinicopathological study.

Authors:  E Montgomery; J R Goldblum; C Fisher
Journal:  Histopathology       Date:  2002-06       Impact factor: 5.087

6.  Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx: a clinicopathologic study. IV. Smooth muscle tumors (leiomyoma, leiomyosarcoma)

Authors:  Y S Fu; K H Perzin
Journal:  Cancer       Date:  1975-05       Impact factor: 6.860

7.  Sinonasal cancer in the Italian national surveillance system: Epidemiology, occupation, and public health implications.

Authors:  Alessandra Binazzi; Marisa Corfiati; Davide Di Marzio; Anna M Cacciatore; Jana Zajacovà; Carolina Mensi; Paolo Galli; Lucia Miligi; Roberto Calisti; Elisa Romeo; Alessandro Franchi; Alessandro Marinaccio
Journal:  Am J Ind Med       Date:  2017-11-07       Impact factor: 2.214

8.  Predictors of survival and recurrence in primary leiomyosarcoma.

Authors:  Rebecca A Gladdy; Li-Xuan Qin; Nicole Moraco; Narasimhan P Agaram; Murray F Brennan; Samuel Singer
Journal:  Ann Surg Oncol       Date:  2013-01-25       Impact factor: 5.344

9.  Radiation-induced leiomyosarcoma of the oropharynx.

Authors:  Jens Pfeiffer; Carsten Christof Boedeker; Gerd Jürgen Ridder; Wolfgang Maier; Gian Kayser
Journal:  Diagn Pathol       Date:  2006-08-22       Impact factor: 2.644

10.  Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT.

Authors:  Fouzia Siraj; Varsha Dalal; Manveen Kaur; Kapil Suri
Journal:  World J Nucl Med       Date:  2016-09
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  1 in total

Review 1.  Rare Diseases of the Nose, the Paranasal Sinuses, and the Anterior Skull Base.

Authors:  Fabian Sommer
Journal:  Laryngorhinootologie       Date:  2021-04-30       Impact factor: 1.057

  1 in total

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