Literature DB >> 29584411

Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy.

Hengrui Liu1, Stuart L Schreiber2,3, Brent R Stockwell1,4.   

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Year:  2018        PMID: 29584411      PMCID: PMC5962875          DOI: 10.1021/acs.biochem.8b00307

Source DB:  PubMed          Journal:  Biochemistry        ISSN: 0006-2960            Impact factor:   3.162


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  5 in total

Review 1.  Lipid homeostasis and regulated cell death.

Authors:  Eran Agmon; Brent R Stockwell
Journal:  Curr Opin Chem Biol       Date:  2017-06-20       Impact factor: 8.822

2.  Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.

Authors:  Vasanthi S Viswanathan; Matthew J Ryan; Harshil D Dhruv; Shubhroz Gill; Ossia M Eichhoff; Brinton Seashore-Ludlow; Samuel D Kaffenberger; John K Eaton; Kenichi Shimada; Andrew J Aguirre; Srinivas R Viswanathan; Shrikanta Chattopadhyay; Pablo Tamayo; Wan Seok Yang; Matthew G Rees; Sixun Chen; Zarko V Boskovic; Sarah Javaid; Cherrie Huang; Xiaoyun Wu; Yuen-Yi Tseng; Elisabeth M Roider; Dong Gao; James M Cleary; Brian M Wolpin; Jill P Mesirov; Daniel A Haber; Jeffrey A Engelman; Jesse S Boehm; Joanne D Kotz; Cindy S Hon; Yu Chen; William C Hahn; Mitchell P Levesque; John G Doench; Michael E Berens; Alykhan F Shamji; Paul A Clemons; Brent R Stockwell; Stuart L Schreiber
Journal:  Nature       Date:  2017-07-05       Impact factor: 49.962

Review 3.  Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Authors:  Brent R Stockwell; José Pedro Friedmann Angeli; Hülya Bayir; Ashley I Bush; Marcus Conrad; Scott J Dixon; Simone Fulda; Sergio Gascón; Stavroula K Hatzios; Valerian E Kagan; Kay Noel; Xuejun Jiang; Andreas Linkermann; Maureen E Murphy; Michael Overholtzer; Atsushi Oyagi; Gabriela C Pagnussat; Jason Park; Qitao Ran; Craig S Rosenfeld; Konstantin Salnikow; Daolin Tang; Frank M Torti; Suzy V Torti; Shinya Toyokuni; K A Woerpel; Donna D Zhang
Journal:  Cell       Date:  2017-10-05       Impact factor: 41.582

4.  Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.

Authors:  Matthew J Hangauer; Vasanthi S Viswanathan; Matthew J Ryan; Dhruv Bole; John K Eaton; Alexandre Matov; Jacqueline Galeas; Harshil D Dhruv; Michael E Berens; Stuart L Schreiber; Frank McCormick; Michael T McManus
Journal:  Nature       Date:  2017-11-01       Impact factor: 49.962

5.  Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.

Authors:  Kari R Fischer; Anna Durrans; Sharrell Lee; Jianting Sheng; Fuhai Li; Stephen T C Wong; Hyejin Choi; Tina El Rayes; Seongho Ryu; Juliane Troeger; Robert F Schwabe; Linda T Vahdat; Nasser K Altorki; Vivek Mittal; Dingcheng Gao
Journal:  Nature       Date:  2015-11-11       Impact factor: 49.962

  5 in total
  22 in total

1.  Small Molecule Regulators of Ferroptosis.

Authors:  Sylvain Debieu; Stéphanie Solier; Ludovic Colombeau; Antoine Versini; Fabien Sindikubwabo; Alison Forrester; Sebastian Müller; Tatiana Cañeque; Raphaël Rodriguez
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 2.  Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death.

Authors:  V E Kagan; Y Y Tyurina; W Y Sun; I I Vlasova; H Dar; V A Tyurin; A A Amoscato; R Mallampalli; P C A van der Wel; R R He; A A Shvedova; D I Gabrilovich; H Bayir
Journal:  Free Radic Biol Med       Date:  2019-12-25       Impact factor: 7.376

Review 3.  Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.

Authors:  José Pedro Friedmann Angeli; Dmitri V Krysko; Marcus Conrad
Journal:  Nat Rev Cancer       Date:  2019-07       Impact factor: 60.716

4.  Knockdown of anti-silencing function 1B histone chaperone induces cell apoptosis via repressing PI3K/Akt pathway in prostate cancer.

Authors:  Guangye Han; Xinjun Zhang; Pei Liu; Quanfeng Yu; Zeyu Li; Qinnan Yu; Xiaoxia Wei
Journal:  Int J Oncol       Date:  2018-08-16       Impact factor: 5.650

Review 5.  Ferroptosis, a new form of cell death: opportunities and challenges in cancer.

Authors:  Yanhua Mou; Jun Wang; Jinchun Wu; Dan He; Chunfang Zhang; Chaojun Duan; Bin Li
Journal:  J Hematol Oncol       Date:  2019-03-29       Impact factor: 17.388

6.  Ferroptosis-related genes are potential prognostic molecular markers for patients with colorectal cancer.

Authors:  Yanliang Liu; Fengqin Guo; Wenyi Guo; Yatao Wang; Wei Song; Tao Fu
Journal:  Clin Exp Med       Date:  2021-03-06       Impact factor: 3.984

7.  A Novel Ferroptosis-Related Biomarker Signature to Predict Overall Survival of Esophageal Squamous Cell Carcinoma.

Authors:  Jiahang Song; Yanhu Liu; Xiang Guan; Xun Zhang; Wenda Yu; Qingguo Li
Journal:  Front Mol Biosci       Date:  2021-07-05

8.  Identification and Validation of an 11-Ferroptosis Related Gene Signature and Its Correlation With Immune Checkpoint Molecules in Glioma.

Authors:  Zhuohui Chen; Tong Wu; Zhouyi Yan; Mengqi Zhang
Journal:  Front Cell Dev Biol       Date:  2021-06-23

9.  Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.

Authors:  Han-Jie Liu; Hui-Min Hu; Guan-Zhang Li; Ying Zhang; Fan Wu; Xiu Liu; Kuan-Yu Wang; Chuan-Bao Zhang; Tao Jiang
Journal:  Front Cell Dev Biol       Date:  2020-07-09

10.  iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4.

Authors:  Delin Chen; Bo Chu; Xin Yang; Zhaoqi Liu; Ying Jin; Ning Kon; Raul Rabadan; Xuejun Jiang; Brent R Stockwell; Wei Gu
Journal:  Nat Commun       Date:  2021-06-15       Impact factor: 14.919

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