Takeshi Kera1,2, Hisashi Kawai1, Hirohiko Hirano3, Motonaga Kojima4, Yutaka Watanabe3, Yoshinori Fujiwara5, Kazushige Ihara6, Shuichi Obuchi1. 1. Research Team for Human Care, University of Tokyo Health Sciences, Tokyo, Japan. 2. Department of Rehabilitation, Japanese Red Cross Ogawa Hospital, Saitama, Japan. 3. Research Team for Promoting Independence of the Elderly, University of Tokyo Health Sciences, Tokyo, Japan. 4. Department of Physical Therapy, University of Tokyo Health Sciences, Tokyo, Japan. 5. Research Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. 6. Department of Public Health, School of Medicine, Toho University, Tokyo, Japan.
Abstract
AIM: Diabetes is associated with not only cardiovascular and cerebrovascular disease, but also reductions in physical and cognitive function. The purpose of the present study was to determine whether muscle strength, walking ability and balance declined in Japanese community-dwelling older adults with diabetes or prediabetes. METHODS: We analyzed data from comprehensive health checkups carried out for 1689 individuals (710 men, 979 women; mean age 71.4 ± 5.6 years) between 2011 and 2016. Participants were divided into three groups: no diabetes (non-history of diabetes and glycated hemoglobin level <5.7%), prediabetes (non-history of diabetes, but glycated hemoglobin level was 5.7-6.4%) and diabetes (history of diabetes or glycated hemoglobin level >6.4%). Physical and cognitive function were compared between groups after adjusting for covariates. RESULTS: Participants with diabetes showed higher levels of obesity, comorbidity, gonarthrosis, and body fat, and lower levels of physical function relative to those observed in participants with prediabetes or no diabetes. After adjusting covariates, participants with diabetes showed significantly lower grip strength (P < 0.010), slower walking speed (P < 0.005), longer Timed Up and Go test time (P < 0.007) and less time spent standing on one foot (P < 0.001) relative to those with no diabetes, but not those with prediabetes. CONCLUSIONS: Significant functional decline was observed in community-dwelling older adults with diabetes, but not in those with prediabetes. Prevention of the progression of prediabetes to diabetes is important in avoiding reductions in physical function. Geriatr Gerontol Int 2018; 18: 1031-1037.
AIM: Diabetes is associated with not only cardiovascular and cerebrovascular disease, but also reductions in physical and cognitive function. The purpose of the present study was to determine whether muscle strength, walking ability and balance declined in Japanese community-dwelling older adults with diabetes or prediabetes. METHODS: We analyzed data from comprehensive health checkups carried out for 1689 individuals (710 men, 979 women; mean age 71.4 ± 5.6 years) between 2011 and 2016. Participants were divided into three groups: no diabetes (non-history of diabetes and glycated hemoglobin level <5.7%), prediabetes (non-history of diabetes, but glycated hemoglobin level was 5.7-6.4%) and diabetes (history of diabetes or glycated hemoglobin level >6.4%). Physical and cognitive function were compared between groups after adjusting for covariates. RESULTS:Participants with diabetes showed higher levels of obesity, comorbidity, gonarthrosis, and body fat, and lower levels of physical function relative to those observed in participants with prediabetes or no diabetes. After adjusting covariates, participants with diabetes showed significantly lower grip strength (P < 0.010), slower walking speed (P < 0.005), longer Timed Up and Go test time (P < 0.007) and less time spent standing on one foot (P < 0.001) relative to those with no diabetes, but not those with prediabetes. CONCLUSIONS: Significant functional decline was observed in community-dwelling older adults with diabetes, but not in those with prediabetes. Prevention of the progression of prediabetes to diabetes is important in avoiding reductions in physical function. Geriatr Gerontol Int 2018; 18: 1031-1037.
Authors: Aqeel M Alenazi; Bader A Alqahtani; Vishal Vennu; Mohammed M Alshehri; Ahmad D Alanazi; Saud M Alrawaili; Kamlesh Khunti; Neil A Segal; Saad M Bindawas Journal: Int J Environ Res Public Health Date: 2021-04-21 Impact factor: 3.390
Authors: Aqeel M Alenazi; Mohammed M Alshehri; Shaima Alothman; Bader A Alqahtani; Jason Rucker; Neena K Sharma; Saad M Bindawas; Patricia M Kluding Journal: Phys Ther Date: 2020-10-30