Literature DB >> 29582175

Exogenous surfactant as a bridge to prolonged "total lung rest" in severely injured patient during extracorporeal membrane oxygenation.

Peter Sklienka1, Jan Maca2,3, Filip Bursa2,3, Jan Neiser2,3, Roman Kula2,3, Marcela Kanova2,3, Tomas Danek4, Pavel Sevcik2,3.   

Abstract

We report a case of a 20-year-old male patient suffering from motorcycle accident complicated by rapid development of severe refractory hypoxemia and hypercapnia due to serious bilateral lung contusions and lacerations. Positive pressure mechanical ventilation induced pressure-dependent massive air leak from disrupted pulmonary tissue. Simultaneous implementation of veno-venous extracorporeal membrane oxygenation together with surfactant application allowed prolonged disconnection of patient from mechanical ventilation ("total lung rest" mode). Despite considerable areas of nonaerated tissue on computed tomography prior to the disconnection from mechanical ventilation, almost total functional recovery of lungs was eventually achieved.

Entities:  

Keywords:  Acute respiratory distress syndrome; Exogenous surfactant; Extracorporeal membrane oxygenation; Total lung rest

Mesh:

Substances:

Year:  2018        PMID: 29582175     DOI: 10.1007/s10047-018-1037-2

Source DB:  PubMed          Journal:  J Artif Organs        ISSN: 1434-7229            Impact factor:   1.731


  8 in total

1.  Selective medicated (saline + natural surfactant) bronchoalveolar lavage in unilateral lung contusion. A clinical randomized controlled trial.

Authors:  Giuseppe A Marraro; Carmelo Denaro; Claudio Spada; Marco Luchetti; Carla Giansiracusa
Journal:  J Clin Monit Comput       Date:  2009-12-13       Impact factor: 2.502

2.  Mechanical ventilation management during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a retrospective international multicenter study.

Authors:  Matthieu Schmidt; Claire Stewart; Michael Bailey; Ania Nieszkowska; Joshua Kelly; Lorna Murphy; David Pilcher; D James Cooper; Carlos Scheinkestel; Vincent Pellegrino; Paul Forrest; Alain Combes; Carol Hodgson
Journal:  Crit Care Med       Date:  2015-03       Impact factor: 7.598

3.  Mechanical ventilation during extracorporeal membrane oxygenation. An international survey.

Authors:  Jonathan D Marhong; Teagan Telesnicki; Laveena Munshi; Lorenzo Del Sorbo; Michael Detsky; Eddy Fan
Journal:  Ann Am Thorac Soc       Date:  2014-07

4.  The effect of exogenous surfactant in patients with lung contusions and acute lung injury.

Authors:  I Tsangaris; E Galiatsou; E Kostanti; G Nakos
Journal:  Intensive Care Med       Date:  2007-03-22       Impact factor: 17.440

5.  Local effect of lung contusion on lung surfactant composition in multiple trauma patients.

Authors:  M Aufmkolk; R Fischer; G Voggenreiter; C Kleinschmidt; K P Schmit-Neuerburg; U Obertacke
Journal:  Crit Care Med       Date:  1999-08       Impact factor: 7.598

6.  Exogenous surfactant as a component of complex non-ECMO therapy of ARDS caused by influenza A virus (2009 H1N1).

Authors:  R Kula; J Maca; P Sklienka; J Tichy; P Szturz; J Jahoda; D Czerny; V Chylek; P Sukenik
Journal:  Bratisl Lek Listy       Date:  2011       Impact factor: 1.278

Review 7.  Mechanical ventilation during extracorporeal membrane oxygenation.

Authors:  Matthieu Schmidt; Vincent Pellegrino; Alain Combes; Carlos Scheinkestel; D Jamie Cooper; Carol Hodgson
Journal:  Crit Care       Date:  2014-01-21       Impact factor: 9.097

8.  Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis : Mechanical ventilation during ECMO.

Authors:  Ary Serpa Neto; Matthieu Schmidt; Luciano C P Azevedo; Thomas Bein; Laurent Brochard; Gernot Beutel; Alain Combes; Eduardo L V Costa; Carol Hodgson; Christian Lindskov; Matthias Lubnow; Catherina Lueck; Andrew J Michaels; Jose-Artur Paiva; Marcelo Park; Antonio Pesenti; Tài Pham; Michael Quintel; V Marco Ranieri; Michael Ried; Roberto Roncon-Albuquerque; Arthur S Slutsky; Shinhiro Takeda; Pier Paolo Terragni; Marie Vejen; Steffen Weber-Carstens; Tobias Welte; Marcelo Gama de Abreu; Paolo Pelosi; Marcus J Schultz
Journal:  Intensive Care Med       Date:  2016-09-01       Impact factor: 17.440

  8 in total

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