| Literature DB >> 2958107 |
R J Boegman1, R Metcalf, R J Riopelle, S K Ludwin.
Abstract
Injections of quinolinic acid (QUIN) alone or combinations of QUIN with dipicolinic acid, Mg2+ or 3,4-diaminopyridine were made into the nucleus basalis magnocellularis of the rat. Choline acetyltransferase activity in the cortex decreased following injections of QUIN and this was antagonized by co-injections of QUIN with dipicolinic acid or Mg2+. Co-injections of QUIN with 3,4-diaminopyridine increased the neurotoxicity of quinolinic acid, while diaminopyridine alone was not toxic.Entities:
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Year: 1987 PMID： 2958107 DOI： 10.1016/0006-8993(87)90456-2
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252