BACKGROUND: The aim of the study was to provide an isotemporal substitution model to predict how changes in physical behavior may affect the cardiovascular parameters (CVPs) of older adults. METHODS: Participants wore a thigh-mounted accelerometer for 7 days. Phenotype of the carotid, brachial, and popliteal artery was conducted using ultrasound. Isotemporal substitution was used to simulate the degree to which replacing 1 hour of physical behavior with another would affect CVP. RESULTS: Substitution of sedentary behavior with Standing and sporadic moderate- to vigorous-intensity physical activity (MVPA accumulated in bouts <10 min) would reduce resting heart rate [-6.20 beats per minute (-12.1 to -0.22) and -3.72 beats per minute (-7.01 to -0.44), respectively]. Substitution of sedentary behavior with light-intensity physical activity would reduce carotid artery diameter [-0.54 mm (-1.00 to -0.07)]. Substitution of Standing with sporadic MVPA would increase popliteal artery diameter [1.31 mm (0.11 to 2.51)]. CONCLUSIONS: Our modeling suggests that an accumulation of MVPA bouts that are shorter than the recommended 10-minute minimum may still improve CVP, with lower intensity physical activity also influencing CVP. Our findings are a promising avenue for lifestyle interventions in older adults to reduce the aging effects on CVP for those who cannot engage or sustain sufficient MVPA.
BACKGROUND: The aim of the study was to provide an isotemporal substitution model to predict how changes in physical behavior may affect the cardiovascular parameters (CVPs) of older adults. METHODS:Participants wore a thigh-mounted accelerometer for 7 days. Phenotype of the carotid, brachial, and popliteal artery was conducted using ultrasound. Isotemporal substitution was used to simulate the degree to which replacing 1 hour of physical behavior with another would affect CVP. RESULTS: Substitution of sedentary behavior with Standing and sporadic moderate- to vigorous-intensity physical activity (MVPA accumulated in bouts <10 min) would reduce resting heart rate [-6.20 beats per minute (-12.1 to -0.22) and -3.72 beats per minute (-7.01 to -0.44), respectively]. Substitution of sedentary behavior with light-intensity physical activity would reduce carotid artery diameter [-0.54 mm (-1.00 to -0.07)]. Substitution of Standing with sporadic MVPA would increase popliteal artery diameter [1.31 mm (0.11 to 2.51)]. CONCLUSIONS: Our modeling suggests that an accumulation of MVPA bouts that are shorter than the recommended 10-minute minimum may still improve CVP, with lower intensity physical activity also influencing CVP. Our findings are a promising avenue for lifestyle interventions in older adults to reduce the aging effects on CVP for those who cannot engage or sustain sufficient MVPA.
Authors: Abdullah Bandar Alansare; Bethany Barone Gibbs; Claudia Holzman; J Richard Jennings; Christopher E Kline; Elizabeth Nagle; Janet M Catov Journal: Int J Behav Med Date: 2022-07-11
Authors: Declan J Ryan; Jorgen A Wullems; Georgina K Stebbings; Christopher I Morse; Claire E Stewart; Gladys L Onambele-Pearson Journal: PLoS One Date: 2018-04-19 Impact factor: 3.240
Authors: Stuart J H Biddle; Jason A Bennie; Katrien De Cocker; David Dunstan; Paul A Gardiner; Genevieve N Healy; Brigid Lynch; Neville Owen; Charlotte Brakenridge; Wendy Brown; Matthew Buman; Bronwyn Clark; Ing-Mari Dohrn; Mitch Duncan; Nicholas Gilson; Tracy Kolbe-Alexander; Toby Pavey; Natasha Reid; Corneel Vandelanotte; Ineke Vergeer; Grace E Vincent Journal: Int J Environ Res Public Health Date: 2019-11-27 Impact factor: 3.390