Eline S de Bruïne1,2, Esmee M Reijnierse1,3, Marijke C Trappenburg1,4, Jantsje H Pasma5, Oscar J de Vries6, Carel G M Meskers7,8, Andrea B Maier8,3. 1. Department of Internal Medicine, Section of Gerontology and Geriatrics, VU University Medical Center Amsterdam, Amsterdam, the Netherlands. 2. Department of Geriatrics, Westfriesgasthuis, Hoorn, the Netherlands. 3. Department of Medicine and Aged Care, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Australia. 4. Department of Internal Medicine, Amstelland Hospital, Amstelveen, the Netherlands. 5. Department of Biomechanical Engineering, Delft University of Technology, Delft, the Netherlands. 6. Department of Internal Medicine, OLVG Hospital, Amsterdam, the Netherlands. 7. Department of Rehabilitation Medicine, VU University Medical Center Amsterdam, Amsterdam, the Netherlands. 8. Department of Human Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, the Netherlands.
Abstract
BACKGROUND AND PURPOSE: Orthostatic hypotension (OH), a blood pressure drop after postural change, is a highly prevalent and disabling syndrome in older adults. Yet, the association between physical performance and OH is not clearly established. The aim of this study was to determine whether different types of physical performance are associated with OH in a clinically relevant population of geriatric outpatients. METHODS: This cross-sectional study included 280 geriatric outpatients (mean age: 82.2 years, standard deviation: 7.1). Orthostatic hypotension was determined using intermittently measured blood pressure and continuously measured blood pressure in a random subgroup of 58 patients. Physical performance was classified into a dynamic type (4-m Walk Test, Chair Stand Test, and Timed Up and Go test) and a static type (standing balance tests, handgrip strength). Associations were analyzed using logistic regression models with adjustments for age, sex, weight, and height. RESULTS: Diminished physical performance on the Chair Stand Test was associated with OH measured intermittently. Diminished physical performance on all dynamic physical domains (4-m Walk Test, Chair Stand Test, and Timed Up and Go test) was associated with OH measured continuously. Static physical performance was not significantly associated with OH. CONCLUSION: Dynamic physical performance tests with a substantial postural change and center of mass displacement were significantly associated with OH. The influence of physical performance on OH in daily routine activities should be further explored to establish counteracting interventions.
BACKGROUND AND PURPOSE:Orthostatic hypotension (OH), a blood pressure drop after postural change, is a highly prevalent and disabling syndrome in older adults. Yet, the association between physical performance and OH is not clearly established. The aim of this study was to determine whether different types of physical performance are associated with OH in a clinically relevant population of geriatric outpatients. METHODS: This cross-sectional study included 280 geriatric outpatients (mean age: 82.2 years, standard deviation: 7.1). Orthostatic hypotension was determined using intermittently measured blood pressure and continuously measured blood pressure in a random subgroup of 58 patients. Physical performance was classified into a dynamic type (4-m Walk Test, Chair Stand Test, and Timed Up and Go test) and a static type (standing balance tests, handgrip strength). Associations were analyzed using logistic regression models with adjustments for age, sex, weight, and height. RESULTS: Diminished physical performance on the Chair Stand Test was associated with OH measured intermittently. Diminished physical performance on all dynamic physical domains (4-m Walk Test, Chair Stand Test, and Timed Up and Go test) was associated with OH measured continuously. Static physical performance was not significantly associated with OH. CONCLUSION: Dynamic physical performance tests with a substantial postural change and center of mass displacement were significantly associated with OH. The influence of physical performance on OH in daily routine activities should be further explored to establish counteracting interventions.
Authors: Keenan A Ramsey; Carel G M Meskers; Marijke C Trappenburg; Sjors Verlaan; Esmee M Reijnierse; Anna C Whittaker; Andrea B Maier Journal: Aging Clin Exp Res Date: 2019-08-19 Impact factor: 3.636
Authors: Elena M Christopoulos; Jennifer Tran; Sarah L Hillebrand; Peter W Lange; Rebecca K Iseli; Carel G M Meskers; Andrea B Maier Journal: Int J Cardiol Hypertens Date: 2020-12-08
Authors: Jennifer Tran; Arjen Mol; Rebecca K Iseli; Wen Kwang Lim; Carel G M Meskers; Andrea B Maier Journal: Gerontology Date: 2022-01-17 Impact factor: 5.597
Authors: Arjen Mol; Esmee M Reijnierse; Marijke C Trappenburg; Richard J A van Wezel; Andrea B Maier; Carel G M Meskers Journal: J Am Heart Assoc Date: 2018-11-06 Impact factor: 5.501
Authors: John D O'Connor; Matthew D L O'Connell; Silvin P Knight; Louise Newman; Orna A Donoghue; Rose Anne Kenny Journal: J Gerontol A Biol Sci Med Sci Date: 2022-06-01 Impact factor: 6.591