| Literature DB >> 29577125 |
Anaëlle Doerflinger1, Nam Nguyen Quang, Edmond Gravel, Guillaume Pinna, Marie Vandamme, Frédéric Ducongé, Eric Doris.
Abstract
Polydiacetylene micelles were functionalized with controlled amounts of biotin using bioorthogonal click chemistry. The biotinylated micelles were evaluated in the selective targeting of the MCF-7 cancerous cell line and were shown to be readily internalized. The efficiency of the cellular uptake was correlated to the density of grafted biotin.Entities:
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Year: 2018 PMID: 29577125 DOI: 10.1039/c8cc00553b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222