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Literature DB >> 2957598

Insulin-like growth factor II receptor as a multifunctional binding protein.

D O Morgan, J C Edman, D N Standring, V A Fried, M C Smith, R A Roth, W J Rutter.

Abstract

The primary structure of human insulin-like growth factor II receptor, predicted from the complementary DNA sequence, reveals a transmembrane receptor molecule with a large extracellular domain made up of fifteen repeat sequences and a small region homologous to the collagen-binding domain of fibronectin. The structural and biochemical features of the IGF-II receptor appear identical to those of the cation-independent mannose-6-phosphate receptor.

Entities: Gene Species

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Year: 1987 PMID： 2957598 DOI： 10.1038/329301a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

162 in total

1. Platelet-derived growth factor is a principal inductive factormodulating mannose 6-phosphate/insulin-like growth factor-II receptorgene expression via a distal E-box in activated hepatic stellate cells.

Authors: J A Weiner; A Chen; B H Davis
Journal: Biochem J Date: 2000-01-15 Impact factor: 3.857

2. Expression of insulin like growth factor II and its receptor in hepatocellular carcinogenesis.

Authors: Z R Fan; D H Yang; J Cui; H R Qin; C C Huang
Journal: World J Gastroenterol Date: 2001-04 Impact factor: 5.742

3. Origin of fibronectin type II (FN2) modules: structural analyses of distantly-related members of the kringle family idey the kringle domain of neurotrypsin as a potential link between FN2 domains and kringles.

Authors: O A Ozhogina; M Trexler; L Bányai; M Llinás; L Patthy
Journal: Protein Sci Date: 2001-10 Impact factor: 6.725

10. High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/insulin-like growth factor II receptor.

Authors: Michelle A Hartman; Jodi L Kreiling; James C Byrd; Richard G MacDonald
Journal: FEBS J Date: 2009-02-19 Impact factor: 5.542

Insulin-like growth factor II receptor as a multifunctional binding protein.

1. Platelet-derived growth factor is a principal inductive factormodulating mannose 6-phosphate/insulin-like growth factor-II receptorgene expression via a distal E-box in activated hepatic stellate cells.

2. Expression of insulin like growth factor II and its receptor in hepatocellular carcinogenesis.

3. Origin of fibronectin type II (FN2) modules: structural analyses of distantly-related members of the kringle family idey the kringle domain of neurotrypsin as a potential link between FN2 domains and kringles.

4. Keys to the hidden treasures of the mannose 6-phosphate/insulin-like growth factor 2 receptor.

Review 5. The insulin-like growth factor family of ligands, receptors, and binding proteins.

Review 6. Interactions of pro-cathepsin D and IGF-II on the mannose-6-phosphate/IGF-II receptor.

7. Holistic Healing Through Herbs: Effectiveness of Aloe Vera on Post Extraction Socket Healing.

Review 8. Insulin and insulin-like growth factor receptors in the nervous system.

9. Antibody to type I insulinlike growth factor receptor inhibits growth of Wilms' tumor in culture and in athymic mice.

10. High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/insulin-like growth factor II receptor.