Finding meaning in suffering?-Meaning making and psychological adjustment over the course of a breast cancer disease.

This study aimed to explore individual meaning systems in the course of a breast cancer disease to test the assumed positive relation between meaning and well-being and to investigate the relationship between post-traumatic growth and well-being. A total of 65 patients with breast cancer were examined 1 year after initial treatment and another year follow-up. Questionnaires addressed meaning in life (MLQ), anxiety and depression (HADS), satisfaction with life (SWLS), health-related quality of life (EQ-5D, EORTC) and post-traumatic growth (PTGI). Personal meaning systems were assessed using a qualitative method. In the personal meaning systems with well-being and relationships as the most frequently named meaning categories, the experienced gains far outweigh the losses sustained as a result of the disease. A stronger sense of meaning was related to lower levels of anxiety and depression, a higher level of satisfaction with life and better health-related functioning. Well-being and post-traumatic growth were mostly independent. Reported losses were strongly related to a poorer well-being. Cancer can induce a process of personal growth, and a strong sense of purpose could facilitate psychological adjustment. The often claimed correlation of post-traumatic growth and a better psychological adjustment is still lacking clear evidence, whereas losses proofed to be crucial.