Ariadna Graells-Sans1, Gemma Serral2, Rosa Puigpinós-Riera3. 1. Agència de Salut Pública de Barcelona (ASPB), Barcelona, Catalonia, Spain; Campus Docent Sant Joan de Déu - Fundació privada, Barcelona, Catalonia, Spain. Electronic address: agraells@santjoandedeu.edu.es. 2. Agència de Salut Pública de Barcelona (ASPB), Barcelona, Catalonia, Spain; CIBER de Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain; Institut de Recerca Biomèdica Sant Pau (IIB St. Pau), Barcelona, Catalonia, Spain. Electronic address: gserral@aspb.cat. 3. Agència de Salut Pública de Barcelona (ASPB), Barcelona, Catalonia, Spain; CIBER de Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain; Institut de Recerca Biomèdica Sant Pau (IIB St. Pau), Barcelona, Catalonia, Spain. Electronic address: rpuigpi@aspb.cat.
Abstract
BACKGROUND: Breast cancer is a challenge for women's health-related quality of life (QoL), compromising their physical health and emotional well-being. QoL is equally distributed among different social groups. The aim of this study to analyze the impact of clinical characteristics and social determinants of health on the QoL of a cohort of women diagnosed and/or treated for breast cancer between 2003 and 2013 in one of the main hospitals in Barcelona's public health network. METHODS: We performed a descriptive cross-sectional study in a cohort of 2235 women with various stages of breast cancer at different stages of their disease. Data were obtained using questionnaires QLQ-C30 and QLQ-BR23 from the European Organization for Research and Treatment of Cancer (EORTC), which include a set of functional and symptomatic scales. We conducted descriptive and bivariate analysis using the Chi-Square test and adjusted for relevant variables using logistic regression. The dependent variables were the functional scales of QoL and the independent variables were sociodemographic and clinical variables. RESULTS: We observed significant differences for most QoL functions. Women from the most disadvantaged class, those in social isolation, or those who had suffered relapses showed the poorest results for most of the function scales. In contrast, age had differential effects depending on the function studied. CONCLUSIONS: The QoL of women diagnosed with breast cancer is closely linked to both their social and economic status, and to their stage of disease progression. It is necessary to explore interventions that focus on the social determinants of health in order to mitigate their effects on breast cancer survivors' QoL.
BACKGROUND:Breast cancer is a challenge for women's health-related quality of life (QoL), compromising their physical health and emotional well-being. QoL is equally distributed among different social groups. The aim of this study to analyze the impact of clinical characteristics and social determinants of health on the QoL of a cohort of women diagnosed and/or treated for breast cancer between 2003 and 2013 in one of the main hospitals in Barcelona's public health network. METHODS: We performed a descriptive cross-sectional study in a cohort of 2235 women with various stages of breast cancer at different stages of their disease. Data were obtained using questionnaires QLQ-C30 and QLQ-BR23 from the European Organization for Research and Treatment of Cancer (EORTC), which include a set of functional and symptomatic scales. We conducted descriptive and bivariate analysis using the Chi-Square test and adjusted for relevant variables using logistic regression. The dependent variables were the functional scales of QoL and the independent variables were sociodemographic and clinical variables. RESULTS: We observed significant differences for most QoL functions. Women from the most disadvantaged class, those in social isolation, or those who had suffered relapses showed the poorest results for most of the function scales. In contrast, age had differential effects depending on the function studied. CONCLUSIONS: The QoL of women diagnosed with breast cancer is closely linked to both their social and economic status, and to their stage of disease progression. It is necessary to explore interventions that focus on the social determinants of health in order to mitigate their effects on breast cancer survivors' QoL.
Authors: Arjun Sinha; Avni Bavishi; Elizabeth A Hibler; Eric H Yang; Susmita Parashar; Tochukwu Okwuosa; Jeanne M DeCara; Sherry-Ann Brown; Avirup Guha; Diego Sadler; Sadiya S Khan; Sanjiv J Shah; Clyde W Yancy; Nausheen Akhter Journal: Front Cardiovasc Med Date: 2022-05-20
Authors: Antonio Di Meglio; Julie Havas; Arnauld S Gbenou; Elise Martin; Mayssam El-Mouhebb; Barbara Pistilli; Gwenn Menvielle; Agnes Dumas; Sibille Everhard; Anne-Laure Martin; Paul H Cottu; Florence Lerebours; Charles Coutant; Anne Lesur; Olivier Tredan; Patrick Soulie; Laurence Vanlemmens; Florence Joly; Suzette Delaloge; Patricia A Ganz; Fabrice André; Ann H Partridge; Lee W Jones; Stefan Michiels; Ines Vaz-Luis Journal: J Clin Oncol Date: 2022-04-21 Impact factor: 50.717
Authors: Jéssica Alonso-Molero; Trinidad Dierssen-Sotos; Ines Gomez-Acebo; Nerea Fernandez de Larrea Baz; Marcela Guevara; Pilar Amiano; Gemma Castaño-Vinyals; Tania Fernandez-Villa; Victor Moreno; Juan Bayo; Ana Molina-Barceloa; María Fernández-Ortíz; Claudia Suarez-Calleja; Rafael Marcos-Gragera; Xavier Castells; Leire Gil-Majuelo; Eva Ardanaz; Beatriz Pérez-Gómez; Manolis Kogevinas; Marina Pollán; Javier Llorca Journal: Int J Environ Res Public Health Date: 2020-11-13 Impact factor: 3.390