Literature DB >> 29572326

Fuzzy and fast nuclear transport.

Frans A A Mulder1.   

Abstract

Exchange of macromolecules between the cytoplasm and the nucleus of all eukaryotic cells is controlled by nuclear pore complexes, which form a selective permeability barrier. The requirement for rapid but selective transport leads to a "transport paradox." A new experimental study now provides a thermodynamic explanation.
© 2018 Mulder.

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Year:  2018        PMID： 29572326      PMCID： PMC5868272          DOI： 10.1074/jbc.H118.002129

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  5 in total

1.  On the nature of the multivalency effect: a thermodynamic model.

Authors:  Pavel I Kitov; David R Bundle
Journal:  J Am Chem Soc       Date:  2003-12-31       Impact factor: 15.419

Review 2.  The nuclear pore complex: understanding its function through structural insight.

Authors:  Martin Beck; Ed Hurt
Journal:  Nat Rev Mol Cell Biol       Date:  2016-12-21       Impact factor: 94.444

3.  Protein activity regulation by conformational entropy.

Authors:  Shiou-Ru Tzeng; Charalampos G Kalodimos
Journal:  Nature       Date:  2012-08-09       Impact factor: 49.962

4.  Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex.

Authors:  Ryo Hayama; Samuel Sparks; Lee M Hecht; Kaushik Dutta; Jerome M Karp; Christina M Cabana; Michael P Rout; David Cowburn
Journal:  J Biol Chem       Date:  2018-01-26       Impact factor: 5.157

5.  Finding Our Way in the Dark Proteome.

Authors:  Asmit Bhowmick; David H Brookes; Shane R Yost; H Jane Dyson; Julie D Forman-Kay; Daniel Gunter; Martin Head-Gordon; Gregory L Hura; Vijay S Pande; David E Wemmer; Peter E Wright; Teresa Head-Gordon
Journal:  J Am Chem Soc       Date:  2016-07-19       Impact factor: 15.419
  5 in total
  1 in total

1.  Nucleoporins' exclusive amino acid sequence features regulate their transient interaction with and selectivity of cargo complexes in the nuclear pore.

Authors:  Mohaddeseh Peyro; Andrew M Dickson; Mohammad R K Mofrad
Journal:  Mol Biol Cell       Date:  2021-09-02       Impact factor: 4.138
  1 in total

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