| Literature DB >> 29571487 |
Da Eun Yoo1, Kyung Min Jeong1, Se Young Han1, Eun Mi Kim1, Yan Jin1, Jeongmi Lee2.
Abstract
Spent coffee grounds (SCGs) are viewed as a valuable resource for useful bioactive compounds, such as chlorogenic acids and flavonoids, and we suggest an eco-friendly and efficient valorization method. A series of choline chloride-based deep eutectic solvents (DESs) were tested as green extraction solvents for use with ultrasound-assisted extraction. Extraction efficiency was evaluated based on total phenolic content (TPC), total flavonoid content, total chlorogenic acids, and/or anti-oxidant activity. A binary DES named HC-6, which was composed of 1,6-hexanediol:choline chloride (molar ratio 7:1) was designed to produce the highest efficiency. Experimental conditions were screened and optimized for maximized efficiency using a two-level fractional factorial design and a central composite design, respectively. As a result, the proposed method presented significantly enhanced TPC and anti-oxidant activity. In addition, phenolic compounds could be easily recovered from extracts at high recovery yields (>90%) by adsorption chromatography.Entities:
Keywords: Anti-oxidant activity; Deep eutectic solvents; Phenolic compounds; Response surface methodology; Spent coffee grounds; Two-level fractional factorial design
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Year: 2018 PMID： 29571487 DOI： 10.1016/j.foodchem.2018.02.096
Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514