Literature DB >> 29568247

Diabetes Type 2 and Pancreatic Cancer: A History Unfolding.

Andre De Souza1, Khawaja Irfan2, Faisal Masud3, Muhammad Wasif Saif1.   

Abstract

Pancreatic Cancer is the fourth cause of cancer-related deaths in the United States. Up to 80% of pancreatic cancer patients present with either new-onset type 2 diabetes or impaired glucose tolerance at the time of diagnosis. Recent literature suggests that diabetes mellitus type 2 is a risk factor, a manifestation and a prognostic factor for pancreatic cancer. This article is intended to clarify the evidence about diabetes as a risk factor for pancreatic cancer.

Entities:  

Keywords:  Diabetes Mellitus; Hyperinsulinemia; Pancreatic Neoplasms; Prognosis; Type 2

Year:  2016        PMID： 29568247      PMCID： PMC5860818     

Source DB:  PubMed          Journal:  JOP        ISSN： 1590-8577


  65 in total

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Review 2.  Clinical outcome of pancreatic cancer patients with diabetes mellitus: is diabetes a poor prognostic factor? Highlights from the "2010 ASCO Annual Meeting". Chicago, IL, USA. June 4-8, 2010.

Authors:  Soonmo Peter Kang; Muhammad Wasif Saif
Journal:  JOP       Date:  2010-07-05

3.  Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer.

Authors:  Oliver Stoeltzing; Wenbiao Liu; Niels Reinmuth; Fan Fan; Alexander A Parikh; Corazon D Bucana; Douglas B Evans; Gregg L Semenza; Lee M Ellis
Journal:  Am J Pathol       Date:  2003-09       Impact factor: 4.307

4.  Risk of pancreatic cancer in families with Lynch syndrome.

Authors:  Fay Kastrinos; Bhramar Mukherjee; Nabihah Tayob; Fei Wang; Jennifer Sparr; Victoria M Raymond; Prathap Bandipalliam; Elena M Stoffel; Stephen B Gruber; Sapna Syngal
Journal:  JAMA       Date:  2009-10-28       Impact factor: 56.272

5.  Pancreatic cancer-associated diabetes mellitus: prevalence and temporal association with diagnosis of cancer.

Authors:  Suresh T Chari; Cynthia L Leibson; Kari G Rabe; Lawrence J Timmons; Jeanine Ransom; Mariza de Andrade; Gloria M Petersen
Journal:  Gastroenterology       Date:  2007-10-26       Impact factor: 22.682

6.  Cigarette smoking, environmental tobacco smoke exposure and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition.

Authors:  Alina Vrieling; H Bas Bueno-de-Mesquita; Hendriek C Boshuizen; Dominique S Michaud; Marianne T Severinsen; Kim Overvad; Anja Olsen; Anne Tjønneland; Françoise Clavel-Chapelon; Marie-Christine Boutron-Ruault; Rudolf Kaaks; Sabine Rohrmann; Heiner Boeing; Ute Nöthlings; Antonia Trichopoulou; Eftihia Moutsiou; Vardis Dilis; Domenico Palli; Vittorio Krogh; Salvatore Panico; Rosario Tumino; Paolo Vineis; Carla H van Gils; Petra H M Peeters; Eiliv Lund; Inger T Gram; Laudina Rodríguez; Antonio Agudo; Nerea Larrañaga; María-José Sánchez; Carmen Navarro; Aurelio Barricarte; Jonas Manjer; Björn Lindkvist; Malin Sund; Weimin Ye; Sheila Bingham; Kay-Tee Khaw; Andrew Roddam; Tim Key; Paolo Boffetta; Eric J Duell; Mazda Jenab; Valentina Gallo; Elio Riboli
Journal:  Int J Cancer       Date:  2010-05-15       Impact factor: 7.396

7.  Metabolic syndrome and cancer risk.

Authors:  Antonio Russo; Mariangela Autelitano; Luigi Bisanti
Journal:  Eur J Cancer       Date:  2007-12-04       Impact factor: 9.162

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Authors:  J Everhart; D Wright
Journal:  JAMA       Date:  1995 May 24-31       Impact factor: 56.272

Review 9.  The stromal compartments in pancreatic cancer: are there any therapeutic targets?

Authors:  Serena Lunardi; Ruth J Muschel; Thomas B Brunner
Journal:  Cancer Lett       Date:  2013-10-16       Impact factor: 8.679

10.  Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells.

Authors:  Emelie Karnevi; Katarzyna Said; Roland Andersson; Ann H Rosendahl
Journal:  BMC Cancer       Date:  2013-05-10       Impact factor: 4.430
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  6 in total

1.  A cellular and bioinformatics analysis of the SENP1 SUMO isopeptidase in pancreatic cancer.

Authors:  Danielle M Bouchard; Michael J Matunis
Journal:  J Gastrointest Oncol       Date:  2019-10

2.  A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer.

Authors:  Ashley Jermusyk; Jun Zhong; Katelyn E Connelly; Naomi Gordon; Sumeth Perera; Ehssan Abdolalizadeh; Tongwu Zhang; Aidan O'Brien; Jason W Hoskins; Irene Collins; Daina Eiser; Chen Yuan; Harvey A Risch; Eric J Jacobs; Donghui Li; Mengmeng Du; Rachael Z Stolzenberg-Solomon; Alison P Klein; Jill P Smith; Brian M Wolpin; Stephen J Chanock; Jianxin Shi; Gloria M Petersen; Christopher J Westlake; Laufey T Amundadottir
Journal:  Am J Hum Genet       Date:  2021-09-23       Impact factor: 11.043

Review 3.  Pancreatic stellate cells - rising stars in pancreatic pathologies.

Authors:  P Hrabák; M Kalousová; T Krechler; T Zima
Journal:  Physiol Res       Date:  2021-12-30       Impact factor: 2.139

4.  Updated risk factors to inform early pancreatic cancer screening and identify high risk patients.

Authors:  Daniel R Principe; Ajay Rana
Journal:  Cancer Lett       Date:  2020-05-08       Impact factor: 9.756

5.  Association between fasting blood glucose levels at admission and overall survival of patients with pancreatic cancer.

Authors:  Mingming Zhang; Xiaoru Hu; Ye Kang; Wanfeng Xu; Xianghong Yang
Journal:  BMC Cancer       Date:  2021-02-06       Impact factor: 4.430

6.  Prenatal diethylstilbestrol exposure and risk of diabetes, gallbladder disease, and pancreatic disorders and malignancies.

Authors:  Rebecca Troisi; Marianne Hyer; Linda Titus; Julie R Palmer; Elizabeth E Hatch; Dezheng Huo; Kjersti M Aagaard; William C Strohsnitter; Robert N Hoover
Journal:  J Dev Orig Health Dis       Date:  2020-10-28       Impact factor: 3.034
  6 in total

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