Literature DB >> 29567993

Unexplored therapeutic opportunities in the human genome.

Tudor I Oprea, Cristian G Bologa, Søren Brunak, Allen Campbell, Gregory N Gan, Anna Gaulton, Shawn M Gomez, Rajarshi Guha, Anne Hersey, Jayme Holmes, Ajit Jadhav, Lars Juhl Jensen, Gary L Johnson, Anneli Karlson, Andrew R Leach, Avi Ma'ayan, Anna Malovannaya, Subramani Mani, Steven L Mathias, Michael T McManus, Terrence F Meehan, Christian von Mering, Daniel Muthas, Dac-Trung Nguyen, John P Overington, George Papadatos, Jun Qin, Christian Reich, Bryan L Roth, Stephan C Schürer, Anton Simeonov, Larry A Sklar, Noel Southall, Susumu Tomita, Ilinca Tudose, Oleg Ursu, Dušica Vidovic, Anna Waller, David Westergaard, Jeremy J Yang, Gergely Zahoránszky-Köhalmi.   

Abstract

This corrects the article DOI: 10.1038/nrd.2018.14.

Entities:  

Year:  2018        PMID: 29567993     DOI: 10.1038/nrd.2018.52

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  17 in total

Review 1.  Exploring the dark genome: implications for precision medicine.

Authors:  Tudor I Oprea
Journal:  Mamm Genome       Date:  2019-07-04       Impact factor: 2.957

Review 2.  Genetic Support for Longevity-Enhancing Drug Targets: Issues, Preliminary Data, and Future Directions.

Authors:  Jamison McCorrison; Thomas Girke; Laura H Goetz; Richard A Miller; Nicholas J Schork
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2019-11-13       Impact factor: 6.053

Review 3.  Molecular pharmacology of metabotropic receptors targeted by neuropsychiatric drugs.

Authors:  Bryan L Roth
Journal:  Nat Struct Mol Biol       Date:  2019-07-03       Impact factor: 15.369

4.  Supervised learning with word embeddings derived from PubMed captures latent knowledge about protein kinases and cancer.

Authors:  Vida Ravanmehr; Hannah Blau; Luca Cappelletti; Tommaso Fontana; Leigh Carmody; Ben Coleman; Joshy George; Justin Reese; Marcin Joachimiak; Giovanni Bocci; Peter Hansen; Carol Bult; Jens Rueter; Elena Casiraghi; Giorgio Valentini; Christopher Mungall; Tudor I Oprea; Peter N Robinson
Journal:  NAR Genom Bioinform       Date:  2021-12-08

5.  Identification of Conserved Proteomic Networks in Neurodegenerative Dementia.

Authors:  Vivek Swarup; Timothy S Chang; Duc M Duong; Eric B Dammer; Jingting Dai; James J Lah; Erik C B Johnson; Nicholas T Seyfried; Allan I Levey; Daniel H Geschwind
Journal:  Cell Rep       Date:  2020-06-23       Impact factor: 9.423

6.  Far away from the lamppost.

Authors:  Tudor I Oprea; Lily Jan; Gary L Johnson; Bryan L Roth; Avi Ma'ayan; Stephan Schürer; Brian K Shoichet; Larry A Sklar; Michael T McManus
Journal:  PLoS Biol       Date:  2018-12-11       Impact factor: 9.593

Review 7.  Ion channels as therapeutic antibody targets.

Authors:  Catherine J Hutchings; Paul Colussi; Theodore G Clark
Journal:  MAbs       Date:  2018-12-10       Impact factor: 5.857

Review 8.  Predicting human disease mutations and identifying drug targets from mouse gene knockout phenotyping campaigns.

Authors:  Robert Brommage; David R Powell; Peter Vogel
Journal:  Dis Model Mech       Date:  2019-05-07       Impact factor: 5.758

9.  The Deep Genome Project.

Authors:  K C Kent Lloyd; David J Adams; Gareth Baynam; Arthur L Beaudet; Fatima Bosch; Kym M Boycott; Robert E Braun; Mark Caulfield; Ronald Cohn; Mary E Dickinson; Michael S Dobbie; Ann M Flenniken; Paul Flicek; Sanjeev Galande; Xiang Gao; Anne Grobler; Jason D Heaney; Yann Herault; Martin Hrabě de Angelis; James R Lupski; Stanislas Lyonnet; Ann-Marie Mallon; Fabio Mammano; Calum A MacRae; Roderick McInnes; Colin McKerlie; Terrence F Meehan; Stephen A Murray; Lauryl M J Nutter; Yuichi Obata; Helen Parkinson; Michael S Pepper; Radislav Sedlacek; Je Kyung Seong; Toshihiko Shiroishi; Damian Smedley; Glauco Tocchini-Valentini; David Valle; Chi-Kuang Leo Wang; Sara Wells; Jacqueline White; Wolfgang Wurst; Ying Xu; Steve D M Brown
Journal:  Genome Biol       Date:  2020-02-03       Impact factor: 13.583

10.  Large-scale investigation of the reasons why potentially important genes are ignored.

Authors:  Thomas Stoeger; Martin Gerlach; Richard I Morimoto; Luís A Nunes Amaral
Journal:  PLoS Biol       Date:  2018-09-18       Impact factor: 8.029

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