Aestivalosides A-L, twelve pregnane glycosides from the seeds of Adonis aestivalis.

Eight adonilide (14,20α-epoxy-3β,20-dihydroxy-14β-pregn-5-en-18-oic acid γ-lactone) glycosides, named aestivalosides A-H, and four glycosides of the adonilide derivatives, named aestivalosides I-L, were isolated from the MeOH extract of seeds of Adonis aestivalis. Aestivalosides A-L were previously undescribed compounds, and were structurally characterized using spectroscopic techniques, including two-dimensional NMR, and chemical methods.