Literature DB >> 29567397

Nanopharmaceuticals for wound healing - Lost in translation?

Mukul Ashtikar1, Matthias G Wacker2.   

Abstract

Today, many of the newly developed pharmaceuticals and medical devices take advantage of nanotechnology and with a rising incidence of chronic diseases such as diabetes and cardiovascular disease, the number of patients afflicted globally with non-healing wounds is growing. This has created a requirement for improved therapies and wound care. However, converting the strategies applied in early research into new products is still challenging. Many of them fail to comply with the market requirements. This review discusses the legal and scientific challenges in the design of nanomedicines for wound healing. Are they lost in translation or is there a new generation of therapeutics in the pipeline?
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Advanced wound healing therapies; Biomaterials; Current regulatory perspective; Nanomaterials

Mesh:

Substances:

Year:  2018        PMID: 29567397     DOI: 10.1016/j.addr.2018.03.005

Source DB:  PubMed          Journal:  Adv Drug Deliv Rev        ISSN: 0169-409X            Impact factor:   15.470


  5 in total

Review 1.  Chronic Inflammation in Non-Healing Skin Wounds and Promising Natural Bioactive Compounds Treatment.

Authors:  Priscila Schilrreff; Ulrike Alexiev
Journal:  Int J Mol Sci       Date:  2022-04-28       Impact factor: 6.208

2.  The Impact of Composites with Silicate-Based Glasses and Gold Nanoparticles on Skin Wound Regeneration.

Authors:  Sorin M Mârza; Klara Magyari; Sidonia Bogdan; Mirela Moldovan; Cosmin Peștean; Andras Nagy; Adrian Florin Gal; Flaviu Tăbăran; Robert Cristian Purdoiu; Emilia Licărete; Sorina Suarasan; Lucian Baia; Ionel Papuc
Journal:  Molecules       Date:  2021-01-25       Impact factor: 4.411

3.  Editorial: Interfacial strategies to manipulate tissue interactions for wound healing.

Authors:  Yazhong Bu; Guoming Sun; Da Huang; Fei Yang
Journal:  Front Bioeng Biotechnol       Date:  2022-08-24

Review 4.  Protein-Based Systems for Topical Antibacterial Therapy.

Authors:  Raj Kumar Thapa; Krister Gjestvang Grønlien; Hanne Hjorth Tønnesen
Journal:  Front Med Technol       Date:  2021-06-24

5.  An Update to Dialysis-Based Drug Release Testing-Data Analysis and Validation Using the Pharma Test Dispersion Releaser.

Authors:  Marc-Phillip Mast; Harshvardhan Modh; Julian Knoll; Elena Fecioru; Matthias G Wacker
Journal:  Pharmaceutics       Date:  2021-11-25       Impact factor: 6.321

  5 in total

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