Lene Hymøller Mundbjerg1,2,3, Charlotte Røn Stolberg1,2,3, Stefano Cecere4, Else-Marie Bladbjerg2,5, Peter Funch-Jensen6, Bibi Gram2, Claus Bogh Juhl1,2. 1. Department of Medicine/Endocrinology, Hospital of Southwest Jutland, Esbjerg, Denmark. 2. Department of Regional Health Research, University of Southern Denmark, Odense, Denmark. 3. Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark. 4. Department of Diagnostic Radiology, Copenhagen University Hospital, Herlev, Denmark. 5. Unit for Thrombosis Research, Department of Clinical Biochemistry, Hospital of Southwest Jutland, Esbjerg, Denmark. 6. Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
Abstract
OBJECTIVE: Bariatric surgery results in significant weight loss and reduces cardiovascular morbidity. However, a large variation in postsurgery weight loss is seen. Physical activity promotes weight loss in nonsurgically treated subjects with obesity. The aim of this study was to investigate the effects of 6 months of supervised physical training following Roux-en-Y gastric bypass surgery (RYGB) on body weight and cardiovascular risk markers. METHODS:Sixty participants eligible for RYGB were included. Six months post surgery, the participants were randomly assigned to either twice-weekly supervised physical training sessions in a fitness center (INT) or a control group (CON) for 26 weeks. Before surgery and 6, 12, and 24 months after surgery, the participants underwent an examination program that included anthropometric measurements, blood pressure, heart rate, blood samples, and an abdominal computed tomography scan. RESULTS: RYGB significantly reduced body weight and improved cardiovascular risk markers (all P < 0.01). The supervised physical training intervention resulted in a 4.2-kg (CI: -0.2 to -8.3 kg) lower body weight in INT compared with CON at the study end (P = 0.042). The high-density lipoprotein concentration was significantly higher in INT than in CON at the termination of the intervention, but this was not maintained at the 24-months examination. CONCLUSIONS:Physical training following RYGB improves weight loss and cardiovascular health.
RCT Entities:
OBJECTIVE: Bariatric surgery results in significant weight loss and reduces cardiovascular morbidity. However, a large variation in postsurgery weight loss is seen. Physical activity promotes weight loss in nonsurgically treated subjects with obesity. The aim of this study was to investigate the effects of 6 months of supervised physical training following Roux-en-Y gastric bypass surgery (RYGB) on body weight and cardiovascular risk markers. METHODS: Sixty participants eligible for RYGB were included. Six months post surgery, the participants were randomly assigned to either twice-weekly supervised physical training sessions in a fitness center (INT) or a control group (CON) for 26 weeks. Before surgery and 6, 12, and 24 months after surgery, the participants underwent an examination program that included anthropometric measurements, blood pressure, heart rate, blood samples, and an abdominal computed tomography scan. RESULTS: RYGB significantly reduced body weight and improved cardiovascular risk markers (all P < 0.01). The supervised physical training intervention resulted in a 4.2-kg (CI: -0.2 to -8.3 kg) lower body weight in INT compared with CON at the study end (P = 0.042). The high-density lipoprotein concentration was significantly higher in INT than in CON at the termination of the intervention, but this was not maintained at the 24-months examination. CONCLUSIONS: Physical training following RYGB improves weight loss and cardiovascular health.
Authors: Charlotte Røn Stolberg; Lene Hymøller Mundbjerg; Else-Marie Bladbjerg; Peter Funch-Jensen; Bibi Gram; Claus Bogh Juhl Journal: Qual Life Res Date: 2018-07-25 Impact factor: 4.147
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