Literature DB >> 29565708

Multifaceted interventions improve medication adherence and reduce acute hospitalization rates in medicaid patients prescribed asthma controllers.

Andrea D Gelzer1, Wanzhen Gao2, David Keleti3, Thomas Donia1, Lauren Megargell4, Jeffrey Kreitman5, Karen E Michael1.   

Abstract

OBJECTIVE: To measure the effectiveness of managed care-led interventions in Medicaid subjects with asthma on medication adherence and acute hospitalization in Pennsylvania.
METHODS: A total of 3589 members (age range, 5-64 years) served by two Pennsylvania-based Medicaid managed care plans (southeastern Pennsylvania [SEPA] and Lehigh-Capital/New West Pennsylvania [LCNWPA]) with low adherence rates (proportion of days covered [PDC]; 20%-67%) for asthma controller prescription fills in 2012 were guided through a care continuum by a comprehensive asthma strategy, consisting of adherence-improvement interventions (grouped as general intervention [GI] or personalized intervention [PI] for higher-risk subjects). Medication adherence and acute hospitalization rates (emergency department [ED] and inpatient [IP]) were compared at baseline versus one-year post-intervention using paired t-test or signed-rank tests. Repeated measures analysis of variances detected the interaction effect of time by intervention group after controlling for sociodemographic covariates.
RESULTS: Member profiles in SEPA (n = 2 796) and LCNWPA (n = 793) were racially and ethnically distinct. Both cohorts experienced statistically significant improvements in mean PDC rate (+4.9% and +7.2%; p = 0.01 and p = 0.03, respectively), accompanied by significant reductions in ED visits (asthma-related: -23.0% and -17.5%, respectively; p < 0.01), and IP admissions (asthma-related: -37.1% and -40.0%, respectively; p < 0.01). The PI subcohorts showed significantly greater improvements in mean PDC versus GI subcohorts (p ≤ 0.04), whereas acute hospitalization rates were statistically comparable in the SEPA cohort, despite its greater asthma burden.
CONCLUSIONS: Managed care-led interventions can effectively improve medication adherence and reduce acute hospitalizations in high-risk Medicaid populations.

Entities:  

Keywords:  Emergency department visits; inpatient admissions; managed care; proportion of days covered

Year:  2018        PMID: 29565708     DOI: 10.1080/02770903.2018.1439954

Source DB:  PubMed          Journal:  J Asthma        ISSN: 0277-0903            Impact factor:   2.515


  3 in total

1.  Refill Reminder Preference and Inhaled Corticosteroid Adherence Among Patients with Asthma.

Authors:  Marsha A Raebel; Susan M Shetterly; Glenn K Goodrich; Courtney B Anderson; Bruce G Bender; Nicole M Wagner
Journal:  Perm J       Date:  2020-11

2.  Prevalence and impact of risk factors for poor asthma outcomes in a large, specialist-managed patient cohort: a real-life study.

Authors:  Gábor Tomisa; Alpár Horváth; Zsuzsanna Szalai; Veronika Müller; Lilla Tamási
Journal:  J Asthma Allergy       Date:  2019-09-23

Review 3.  Measuring Medication Adherence in a Population-Based Asthma Administrative Pharmacy Database: A Systematic Review and Meta-Analysis.

Authors:  Michael Asamoah-Boaheng; Kwadwo Osei Bonsu; Jamie Farrell; Alwell Oyet; William K Midodzi
Journal:  Clin Epidemiol       Date:  2021-10-22       Impact factor: 4.790

  3 in total

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