Literature DB >> 29564791

Ex Vivo Functional Evaluation of Synaptic Transmission from Rods to Rod Bipolar Cells in Mice.

Johan Pahlberg1, Anurima Majumder2,3, Nikolai O Artemyev4.   

Abstract

Mice have been widely used as a model organism to study mechanisms of phototransduction and synaptic transmission in the retina. Genetic manipulations and electrophysiological techniques for analysis of photoreceptor and rod bipolar cell function in mice are uniquely advanced. Here, we describe a set of biochemical and electrophysiological techniques for evaluation of synaptic transmission at the rod-rod bipolar cell synapse, which represents the first and key step in the processing of dim-light visual information.

Entities:  

Keywords:  Immunoblot; Immunofluorescence; Patch clamp; Retina; Rod bipolar cell; Rod photoreceptor; Suction electrode

Mesh:

Substances:

Year:  2018        PMID: 29564791      PMCID: PMC6309191          DOI: 10.1007/978-1-4939-7720-8_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  1 in total

1.  Frmpd1 Facilitates Trafficking of G-Protein Transducin and Modulates Synaptic Function in Rod Photoreceptors of Mammalian Retina.

Authors:  Christie K Campla; Ulisse Bocchero; Ryan Strickland; Jacob Nellissery; Jayshree Advani; Irina Ignatova; Dhiraj Srivastava; Angel M Aponte; Yuchen Wang; Jessica Gumerson; Kirill Martemyanov; Nikolai O Artemyev; Johan Pahlberg; Anand Swaroop
Journal:  eNeuro       Date:  2022-10-17
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.