Literature DB >> 29563174

Personalised CFTR pharmacotherapeutic response testing and therapy of cystic fibrosis.

Cormac McCarthy1,2,3, John J Brewington2, Beth Harkness4, John P Clancy2, Bruce C Trapnell1,2,3.   

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Year:  2018        PMID: 29563174     DOI: 10.1183/13993003.02457-2017

Source DB:  PubMed          Journal:  Eur Respir J        ISSN: 0903-1936            Impact factor:   16.671


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  5 in total

1.  Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect.

Authors:  Sharon L Wong; Nikhil T Awatade; Miro A Astore; Katelin M Allan; Michael J Carnell; Iveta Slapetova; Po-Chia Chen; Jeffry Setiadi; Elvis Pandzic; Laura K Fawcett; John R Widger; Renee M Whan; Renate Griffith; Chee Y Ooi; Serdar Kuyucak; Adam Jaffe; Shafagh A Waters
Journal:  Am J Respir Cell Mol Biol       Date:  2022-07       Impact factor: 7.748

Review 2.  Established and novel human translational models to advance cystic fibrosis research, drug discovery, and optimize CFTR-targeting therapeutics.

Authors:  Deborah M Cholon; Martina Gentzsch
Journal:  Curr Opin Pharmacol       Date:  2022-04-21       Impact factor: 4.768

Review 3.  Nasal Epithelial Cell-Based Models for Individualized Study in Cystic Fibrosis.

Authors:  Duncan E Keegan; John J Brewington
Journal:  Int J Mol Sci       Date:  2021-04-24       Impact factor: 5.923

4.  Functional Profiling of CFTR-Directed Therapeutics Using Pediatric Patient-Derived Nasal Epithelial Cell Models.

Authors:  Jeffrey KiHyun Park; Anura Shrivastava; Chengkang Zhang; Brian A Pollok; Walter E Finkbeiner; Elizabeth R Gibb; Ngoc P Ly; Beate Illek
Journal:  Front Pediatr       Date:  2020-09-04       Impact factor: 3.418

5.  Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity.

Authors:  Sharon L Wong; Nikhil T Awatade; Miro A Astore; Katelin M Allan; Michael J Carnell; Iveta Slapetova; Po-Chia Chen; Alexander Capraro; Laura K Fawcett; Renee M Whan; Renate Griffith; Chee Y Ooi; Serdar Kuyucak; Adam Jaffe; Shafagh A Waters
Journal:  iScience       Date:  2021-12-31
  5 in total

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