Literature DB >> 29561692

Antibiotic-Resistant Infection Treatment Costs Have Doubled Since 2002, Now Exceeding $2 Billion Annually.

Kenneth E Thorpe1, Peter Joski2, Kenton J Johnston3.   

Abstract

Antibiotic-resistant infections are a global health care concern. The Centers for Disease Control and Prevention estimates that 23,000 Americans with these infections die each year. Rising infection rates add to the costs of health care and compromise the quality of medical and surgical procedures provided. Little is known about the national health care costs attributable to treating the infections. Using data from the Medical Expenditure Panel Survey, we estimated the incremental health care costs of treating a resistant infection as well as the total national costs of treating such infections. To our knowledge, this is the first national estimate of the costs for treating the infections. We found that antibiotic resistance added $1,383 to the cost of treating a patient with a bacterial infection. Using our estimate of the number of such infections in 2014, this amounts to a national cost of $2.2 billion annually. The need for innovative new infection prevention programs, antibiotics, and vaccines to prevent and treat antibiotic-resistant infections is an international priority.

Entities:  

Keywords:  Cost of Health Care; Health Spending

Mesh:

Year:  2018        PMID: 29561692     DOI: 10.1377/hlthaff.2017.1153

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  37 in total

1.  An informed public's views on reducing antibiotic overuse.

Authors:  Jennifer Richmond; Rikki Mangrum; Grace Wang; Maureen Maurer; Shoshanna Sofaer; Manshu Yang; Kristin L Carman
Journal:  Health Serv Res       Date:  2019-06-06       Impact factor: 3.402

2.  Reduction in antimicrobial use among medical intensive care unit patients during a cluster randomized crossover trial of palliative care consultation.

Authors:  Jason P Burnham; Stephen Chi; Jessica Ma; Maria C Dans; Marin H Kollef
Journal:  Infect Control Hosp Epidemiol       Date:  2019-03-06       Impact factor: 3.254

3.  External Societal Costs of Antimicrobial Resistance in Humans Attributable to Antimicrobial Use in Livestock.

Authors:  Gabriel K Innes; Pranay R Randad; Anton Korinek; Meghan F Davis; Lance B Price; Anthony D So; Christopher D Heaney
Journal:  Annu Rev Public Health       Date:  2020-01-07       Impact factor: 21.981

4.  Using fluorescence microscopy to shed light on the mechanisms of antimicrobial peptides.

Authors:  Anne K Buck; Donald E Elmore; Louise Eo Darling
Journal:  Future Med Chem       Date:  2019-09-13       Impact factor: 3.808

5.  The incremental cost of infections associated with multidrug-resistant organisms in the inpatient hospital setting-A national estimate.

Authors:  Kenton J Johnston; Kenneth E Thorpe; Jesse T Jacob; David J Murphy
Journal:  Health Serv Res       Date:  2019-03-12       Impact factor: 3.402

6.  Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria.

Authors:  Charles G Starr; Jenisha Ghimire; Shantanu Guha; Joseph P Hoffmann; Yihui Wang; Leisheng Sun; Brooke N Landreneau; Zachary D Kolansky; Isabella M Kilanowski-Doroh; Mimi C Sammarco; Lisa A Morici; William C Wimley
Journal:  Proc Natl Acad Sci U S A       Date:  2020-04-02       Impact factor: 11.205

7.  Anti-Sense Antibiotic Agents as Treatment for Bacterial Infections.

Authors:  David B Stewart
Journal:  Surg Infect (Larchmt)       Date:  2018-09-25       Impact factor: 2.150

8.  Theranostic Gallium Siderophore Ciprofloxacin Conjugate with Broad Spectrum Antibiotic Potency.

Authors:  Apurva Pandey; Chloé Savino; Shin Hye Ahn; Zhaoyong Yang; Steven G Van Lanen; Eszter Boros
Journal:  J Med Chem       Date:  2019-10-17       Impact factor: 7.446

Review 9.  Plant Viruses and Bacteriophage-Based Reagents for Diagnosis and Therapy.

Authors:  Sourabh Shukla; He Hu; Hui Cai; Soo-Khim Chan; Christine E Boone; Veronique Beiss; Paul L Chariou; Nicole F Steinmetz
Journal:  Annu Rev Virol       Date:  2020-09-29       Impact factor: 10.431

10.  Association of Antibiotic Treatment With Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated With Systemic Corticosteroids.

Authors:  Mihaela S Stefan; Meng-Shiou Shieh; Kerry A Spitzer; Penelope S Pekow; Jerry A Krishnan; David H Au; Peter K Lindenauer
Journal:  JAMA Intern Med       Date:  2019-03-01       Impact factor: 21.873

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