Literature DB >> 2956124

Identification of the plasma membrane receptor for interleukin-1 on mouse thymoma cells.

C Bron, H R MacDonald.   

Abstract

The plasma membrane receptor for interleukin-1 (IL-1) has been characterized from mouse EL4-6.1 thymoma cells. Following binding of IL-1 to surface labeled EL4-6.1 cells, the IL-1 binding molecule was immuno-precipitated using a rabbit antiserum against the hormone. The putative IL-1 receptor is a membrane-associated glycopeptide of Mr = 82,000 containing probably two or three N-linked glycan units as indicated by its conversion into a Mr = 60,000 polypeptide upon deglycosylation with endo-beta-N-glycosidase F.

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Year:  1987        PMID: 2956124     DOI: 10.1016/0014-5793(87)80254-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  4 in total

1.  The interleukin-1 receptor in Raji human B-lymphoma cells. Molecular characterization and evidence for receptor-mediated activation of gene expression.

Authors:  R Horuk; J A McCubrey
Journal:  Biochem J       Date:  1989-06-15       Impact factor: 3.857

2.  Cloning the interleukin 1 receptor from human T cells.

Authors:  J E Sims; R B Acres; C E Grubin; C J McMahan; J M Wignall; C J March; S K Dower
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

Review 3.  Interleukin 1 receptors and biological responses.

Authors:  C A Dinarello; B D Clark; T Ikejima; A J Puren; N Savage; P M Rosoff
Journal:  Yale J Biol Med       Date:  1990 Mar-Apr

Review 4.  The biological activities of interleukin-1.

Authors:  W E Fibbe; M R Schaafsma; J H Falkenburg; R Willemze
Journal:  Blut       Date:  1989-08
  4 in total

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