Literature DB >> 29561159

Catalytic Enantioselective Birch-Heck Sequence for the Synthesis of Tricyclic Structures with All-Carbon Quaternary Stereocenters.

Andrew T Krasley1, William P Malachowski1, Hannah M Terz1, Sabrina Tran Tien1.   

Abstract

A new enantioselective desymmetrizing Mizoroki-Heck reaction is reported. The process affords high yields and enantioselectivities of tricyclic structures containing all-carbon quaternary stereocenters. The substrates for the reaction are efficiently synthesized from Birch reduction-alkylation of benzoic acid and benzoate esters.

Entities:  

Year:  2018        PMID： 29561159     DOI： 10.1021/acs.orglett.8b00196

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  1 in total

1.  Catalytic Enantioselective Birch-Heck Sequence for the Synthesis of Phenanthridinone Derivatives with an All-Carbon Quaternary Stereocenter.

Authors:  Mary Sexton; William P Malachowski; Glenn P A Yap; Diana Rachii; Greg Feldman; Andrew T Krasley; Zhilin Chen; My Anh Tran; Kalyn Wiley; Alexandra Matei; Samantha Petersen; Sabrina Tran Tien
Journal:  J Org Chem       Date:  2022-01-05       Impact factor: 4.198
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.