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Literature DB >> 29559300

Allogeneic stem cell transplantation for relapsed primary central nervous system lymphoma: Is it feasible?

Erden Atilla¹, Ugur Sahin², Pinar Ataca Atilla², Mustafa Merter², Elif Ozyurek³, Koray Ceyhan⁴, Sinem Civriz Bozdag².

Abstract

Primary central nervous system lymphoma (PCNSL), has an aggressive course and in untreated patients median survival is limited to three months. For relapsed PCNSL, the treatment options are few and results are usually unsatisfactory. Allogeneic Hematopoietic Stem Cell Transplantation (allo-HCT) has been widely used for treatment of relapsed/refractory NHL patients. However there are limited data whether graft versus lymphoma effect can work in PCNSL patients. Here, we present a relapsed refractory PCNSL case treated by allo-HCT.

Entities: Disease Species

Keywords: Allogeneic stem cell transplantation; Graft versus leukemia effect; Primary central nervous system lymphoma

Mesh：

Year: 2018 PMID： 29559300 DOI： 10.1016/j.hemonc.2018.02.001

Source DB: PubMed Journal: Hematol Oncol Stem Cell Ther

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Cited

5 in total

5. CD19 and CD70 Dual-Target Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Relapsed and Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma.

Authors: Sanfang Tu; Xuan Zhou; Zhenling Guo; Rui Huang; Chunyan Yue; Yanjie He; Meifang Li; Yiran Chen; YuChen Liu; Lung-Ji Chang; Yuhua Li
Journal: Front Oncol Date: 2019-12-04 Impact factor: 6.244

5 in total

Allogeneic stem cell transplantation for relapsed primary central nervous system lymphoma: Is it feasible?

1. Allogeneic hematopoietic stem cell transplantation for primary central nervous system lymphoma.

2. Relapsed and refractory primary CNS lymphoma: treatment approaches in routine practice.

3. Diagnosis, prognosis and treatment of primary central nervous system lymphoma in the elderly population (Review).

4. Molecular characteristics of immunocytes infiltration in primary central nervous system lymphoma.

5. CD19 and CD70 Dual-Target Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Relapsed and Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma.