Literature DB >> 29559217

Solitary fibrous tumour/haemangiopericytoma of the spinal cord.

Ana Flores-Justa1, Elena López-García2, Alfredo García-Allut2, Rosa María Reyes-Santías3.   

Abstract

Solitary fibrous tumours/haemangiopericytomas (SFT/HPC) are fibroblastic mesenchymal neoplasms that harbour a genetic fusion of NAB2/STAT6. There are few reported cases in the central nervous system (CNS), of which spinal tumours are minority. We present a case of a 63-year-old woman with progressive paraparesis and a sensory level of T6. On the MRI we detected an intradural extramedullary lesion on T9-T10. We performed a laminectomy with an intraoperative ultrasound study in which we observed a heterogeneous lesion with an infiltrating pattern affecting the medulla at several points, and resection of the lesion. Immunohistological findings revealed positivity for vimentin, CD34 and STAT6; Ki-67 was 2%. A final diagnosis of SFT/HPC with SFT phenotype was made. SFT/HPC of the CNS is a rare neoplasm that should be taken into account in the differential diagnosis of these kinds of lesions, as clinical and MRI findings often lead to errors in diagnostic approach. The support of intraoperative ultrasound can assist in surgical decision-making.
Copyright © 2018 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Dorsal; Haemangiopericytoma; Hemangiopericitoma; MRI; Resonancia magnética; Solitary fibrous tumour; Spinal tumour; Thoracic; Tumor espinal; Tumor fibroso solitario

Mesh:

Substances:

Year:  2018        PMID: 29559217     DOI: 10.1016/j.neucir.2018.01.005

Source DB:  PubMed          Journal:  Neurocirugia (Astur : Engl Ed)        ISSN: 2529-8496


  2 in total

Review 1.  Spinal Solitary Fibrous Tumors: An Original Multicenter Series and Systematic Review of Presentation, Management, and Prognosis.

Authors:  Caroline Apra; Amira El Arbi; Anne-Sophie Montero; Fabrice Parker; Steven Knafo
Journal:  Cancers (Basel)       Date:  2022-06-08       Impact factor: 6.575

2.  A cervical solitary fibrous tumor with intramedullary invasion.

Authors:  Andrea Ciuffi; Christian Saleh; Maria Rosa Terreni; Phillip Jaszczuk; Edvin Zekaj; Claudia Menghetti; Andrea Franzini; Domenico Servello
Journal:  Surg Neurol Int       Date:  2022-08-05
  2 in total

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