Literature DB >> 29557277

A mini review: garlic extract and vascular diseases.

Yuequan Zhu1, Raja Anand2, Xiaokun Geng1,2,3, Yuchuan Ding1,2.   

Abstract

Vascular diseases refer to medical conditions that narrow blood vessels. Narrowed cardiac or cerebral arteries can lead to myocardial infarction or ischemic stroke. Risk factors including atherosclerosis, hypertension, and diabetes may induce either cardiovascular or cerebral complications. Based on current research, garlic favorably affects atherosclerosis, hypertension and diabetes, and helps decrease the risk of myocardial infarction and ischemic stroke. Garlic has been utilized for hundreds of years as a natural health remedy. New research is emerging regarding its effectiveness in treating common diseases, including atherosclerosis, hypertension, and diabetes. The underlying mechanisms by which garlic, and its byproducts, can alter pathophysiology have begun to be elucidated by these studies. Garlic is a prominent topic for future research regarding its potential as an adjuvant to conventional pharmacotherapy for these common health conditions. In this mini-review, we discuss the current state of the literature regarding garlic and its effects in patients with vascular disease. Specifically, we decided to briefly discuss the key points regarding the mechanisms underlying garlic's anti-hypertensive, anti-hyperlipidemic, and hypoglycemic effects. This allows the readers to understand each process while keeping the paper concise. These mechanisms can be further explored in the original articles, at the reader's discretion.

Entities:  

Keywords:  Atherosclerosis; diabetes; hypertension; hypolipidemic and hypocholesterolemic effect; inflammation; oxidative

Mesh:

Substances:

Year:  2018        PMID: 29557277     DOI: 10.1080/01616412.2018.1451269

Source DB:  PubMed          Journal:  Neurol Res        ISSN: 0161-6412            Impact factor:   2.448


  7 in total

1.  Therapeutic potential of Allium Sativum against the Aβ(1-40)-induced oxidative stress and mitochondrial dysfunction in the Wistar rats.

Authors:  Neetu Saini; Monika Kadian; Alka Khera; Aanchal Aggarwal; Anil Kumar
Journal:  Am J Neurodegener Dis       Date:  2021-04-15

2.  Neuroprotective effects of garlic extract on dopaminergic neurons of substantia nigra in a rat model of Parkinson's disease: motor and non-motor outcomes.

Authors:  Maryam Bigham; Abbas Mohammadipour; Mahmoud Hosseini; Amir Mohammad Malvandi; Alireza Ebrahimzadeh-Bideskan
Journal:  Metab Brain Dis       Date:  2021-03-03       Impact factor: 3.584

Review 3.  Relation of Fruits and Vegetables with Major Cardiometabolic Risk Factors, Markers of Oxidation, and Inflammation.

Authors:  Maria Lapuente; Ramon Estruch; Mana Shahbaz; Rosa Casas
Journal:  Nutrients       Date:  2019-10-06       Impact factor: 5.717

Review 4.  Preventing Developmental Origins of Cardiovascular Disease: Hydrogen Sulfide as a Potential Target?

Authors:  Chien-Ning Hsu; You-Lin Tain
Journal:  Antioxidants (Basel)       Date:  2021-02-05

5.  Chemical Composition and Agronomic Traits of Allium sativum and Allium ampeloprasum Leaves and Bulbs and Their Action against Listeria monocytogenes and Other Food Pathogens.

Authors:  Flavio Polito; Giuseppe Amato; Lucia Caputo; Vincenzo De Feo; Florinda Fratianni; Vincenzo Candido; Filomena Nazzaro
Journal:  Foods       Date:  2022-03-29

Review 6.  Chemoprevention effect of the Mediterranean diet on colorectal cancer: Current studies and future prospects.

Authors:  Asma Ismail Mahmod; Shatha Khaled Haif; Ayah Kamal; Israa A Al-Ataby; Wamidh H Talib
Journal:  Front Nutr       Date:  2022-08-04

7.  Antiatherosclerosis Properties of Total Saponins of Garlic in Rats.

Authors:  Qing Miao; Ruihai Wang; Dong Bai; Xin Xue; Jing Xu; Xiaoxin Sun; Limei Liu
Journal:  Evid Based Complement Alternat Med       Date:  2020-02-27       Impact factor: 2.629

  7 in total

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