Gianvincenzo Sparacia1,2, Roberto Cannella3, Vincenzina Lo Re4, Giuseppe Mamone5, Koji Sakai6, Kei Yamada7, Roberto Miraglia5. 1. Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT, Via Tricomi, 5, 90127, Palermo, Italy. gianvincenzo.sparacia@unipa.it. 2. Department of Radiology, University of Palermo, Palermo, Italy. gianvincenzo.sparacia@unipa.it. 3. Department of Radiology, University of Palermo, Palermo, Italy. 4. Neurology Service-IRCCS-ISMETT, Palermo, Italy. 5. Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT, Via Tricomi, 5, 90127, Palermo, Italy. 6. Advanced MR Image Laboratory, Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan. 7. Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Abstract
PURPOSE: To assess brain-core temperature of end-stage liver disease patients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ventricles. MATERIALS AND METHODS: The study group was composed of 19 patients with a model for end-stage liver disease (MELD) score of 23.7 who underwent MR imaging before and after OLT. MR imaging studies were performed with a 1.5T MR scanner. Brain-core temperature (T: °C) was calculated using the following equation from the apparent diffusion coefficient (D) of the cerebrospinal fluid in the lateral ventricles: [Formula: see text] measured with a DWI sequence (b value 1000 s/mm2). We compared brain-core temperature of all patients before and after OLT. RESULTS: Brain-core temperature measurements were successfully taken in all patients before and after OLT. The measured brain-core temperature mean ± standard deviation was 38.67 ± 1.76 °C before OLT and 38.60 ± 0.99 °C after OLT, showing no significant difference (P = 0.643). CONCLUSIONS: Brain-core temperature was stable in patients undergoing OLT. DWI thermometry may provide a supplementary brain biomarker to confirm that cerebral blood flow and metabolism are stable in patients undergoing OLT.
PURPOSE: To assess brain-core temperature of end-stage liver diseasepatients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ventricles. MATERIALS AND METHODS: The study group was composed of 19 patients with a model for end-stage liver disease (MELD) score of 23.7 who underwent MR imaging before and after OLT. MR imaging studies were performed with a 1.5T MR scanner. Brain-core temperature (T: °C) was calculated using the following equation from the apparent diffusion coefficient (D) of the cerebrospinal fluid in the lateral ventricles: [Formula: see text] measured with a DWI sequence (b value 1000 s/mm2). We compared brain-core temperature of all patients before and after OLT. RESULTS: Brain-core temperature measurements were successfully taken in all patients before and after OLT. The measured brain-core temperature mean ± standard deviation was 38.67 ± 1.76 °C before OLT and 38.60 ± 0.99 °C after OLT, showing no significant difference (P = 0.643). CONCLUSIONS: Brain-core temperature was stable in patients undergoing OLT. DWI thermometry may provide a supplementary brain biomarker to confirm that cerebral blood flow and metabolism are stable in patients undergoing OLT.
Authors: T Naegele; W Grodd; R Viebahn; U Seeger; U Klose; D Seitz; S Kaiser; I Mader; J Mayer; W Lauchart; M Gregor; K Voigt Journal: Radiology Date: 2000-09 Impact factor: 11.105
Authors: P S Kamath; R H Wiesner; M Malinchoc; W Kremers; T M Therneau; C L Kosberg; G D'Amico; E R Dickson; W R Kim Journal: Hepatology Date: 2001-02 Impact factor: 17.425
Authors: M A Thomas; A Huda; B Guze; J Curran; M Bugbee; L Fairbanks; Y Ke; T Oshiro; P Martin; F Fawzy Journal: AJR Am J Roentgenol Date: 1998-10 Impact factor: 3.959