Literature DB >> 29555609

Full-Body Analysis of Adult Spinal Deformity Patients' Age-Adjusted Alignment at 1 Year.

Peter G Passias1, Samantha R Horn2, Nicholas J Frangella2, Gregory W Poorman2, Dennis Vasquez-Montes2, Bassel G Diebo3, Cole A Bortz2, Frank A Segreto2, John Y Moon2, Peter L Zhou2, Shaleen Vira2, Akhila Sure2, Bryan Beaubrun2, Jared C Tishelman2, Subaraman Ramchandran2, Cyrus M Jalai2, Wesley Bronson2, Charles Wang2, Virginie Lafage4, Aaron J Buckland2, Thomas J Errico2.   

Abstract

BACKGROUND: Previous studies have built a foundation for understanding compensation in patients with adult spinal deformity (ASD) by using full-body stereographic assessments. These mechanisms, in relation to age-adjusted alignment targets, have yet to be studied fully. The aim of this study was to assess lower-limb compensatory mechanisms of patients failing to meet age-adjusted alignment goals.
METHODS: Patients with ASD ≥40 years with full body baseline and follow-up radiographs were included. Patients were stratified by age (40-65 years, >65 years) and spinopelvic correction. Lower-limb compensation parameters (pelvic shift, hip extension, knee flexion [KA], ankle flexion [AA], and global sagittal angle [GSA]) for patients who matched and failed to match age-adjusted alignment targets were compared with analysis of variance and t-test analysis.
RESULTS: In total, 108 patients were included. At 1 year, AA increased with age in the "match" pelvic tilt (PT) and spinopelvic mismatch (PI-LL) cohorts (PT: AA, 5.6-7.8, P = 0.041; PI-LL: 4.9-8.8, P = 0.026). KA, AA, and GSA increased with age in the "match" sagittal vertical axis (SVA) cohort (KA: 3.8-13.1, P = 0.002; AA: 5.8-10.2, P = 0.008; GSA: 3.9-7.8, P < 0.001), as did KA and GSA in the "match" T1 pelvic angle group (KA: 1.8-8.7, P = 0.020; GSA: 2.6-5.7, P = 0.004).
CONCLUSIONS: Greater compensation captured by KA and GSA was associated with age progression in the "match" SVA and T1 pelvic angle cohorts. In addition, older SVA, PT, and PI-LL "match" cohorts used increased AA, suggesting that ideal postoperative alignment of aged individuals with ASD involves increased compensation.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adult spinal deformity; Age-adjusted alignment; Compensation; Pelvic tilt; Radiographic alignment; Sagittal vertical axis; T1 pelvic angle

Mesh:

Year:  2018        PMID: 29555609     DOI: 10.1016/j.wneu.2018.03.079

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  1 in total

Review 1.  CORR Synthesis: What Is the Evidence for Age-appropriate Alignment Goals in Surgery for Adult Spinal Deformity?

Authors:  Michael Dinizo; Tina Raman
Journal:  Clin Orthop Relat Res       Date:  2021-02-01       Impact factor: 4.755

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.