Rolandas Urbstonaitis1, Maithili Deshpande2, Jennifer Arnoldi2. 1. School of Pharmacy, Southern Illinois University-Edwardsville, Edwardsville, United States. Electronic address: Rurbsto@siue.edu. 2. School of Pharmacy, Southern Illinois University-Edwardsville, Edwardsville, United States.
Abstract
BACKGROUND: Health related quality of life (HRQoL) reflects the impact of a chronic disease, such as asthma, from a patient perspective. Late midlife adults (50-64 years) have been identified by the Centers for Disease Control & Prevention as an important population for healthy aging. OBJECTIVES: To evaluate the factors associated with HRQoL among late midlife adults with asthma. METHODS: This study utilized data from 2012 to 2013 Behavioral Risk Factor Surveillance System Asthma Call Back Survey. Adults with current asthma and 50-64 years of age were included in the study. Independent variables were identified using the Andersen Behavioral Model of Health Services Utilization. HRQoL was defined using 4 domains including self-rated health, physical health, mental health and activity limitation. Descriptive statistics were used to assess sample characteristics. Bivariate and multivariate logistic regression models were used to examine factors associated with the four HRQoL domains. All analyses were stratified by asthma control status. Appropriate survey weights were used to account for the complex survey design. RESULTS: The final sample consisted of 5857 (Weighted: 4 million) late midlife asthmatics, mostly female (66%) and White (72%). About 42% had fair/poor self-rated health, 33% had impaired physical health, 23% had impaired mental health, and 24% experienced activity limitation. Multivariate analyses found that Non-Hispanic African American adults were significantly more likely to report fair/poor self-rated health compared to Whites (Well-controlled asthma OR: 2.2, 95% CI: 1.2-4.1). Adults who experienced any cost barrier were significantly more likely to have activity limitations (Poorly controlled asthma OR: 1.6, 95% CI: 1.1-2.3). Adults with a respiratory comorbidity were more likely to report impaired physical health compared to adults without (Well controlled asthma OR: 1.7, 95% CI: 1.01-2.7). CONCLUSION: Reducing respiratory comorbidities and cost barriers may improve HRQoL in asthmatic late midlife adults.
BACKGROUND: Health related quality of life (HRQoL) reflects the impact of a chronic disease, such as asthma, from a patient perspective. Late midlife adults (50-64 years) have been identified by the Centers for Disease Control & Prevention as an important population for healthy aging. OBJECTIVES: To evaluate the factors associated with HRQoL among late midlife adults with asthma. METHODS: This study utilized data from 2012 to 2013 Behavioral Risk Factor Surveillance System Asthma Call Back Survey. Adults with current asthma and 50-64 years of age were included in the study. Independent variables were identified using the Andersen Behavioral Model of Health Services Utilization. HRQoL was defined using 4 domains including self-rated health, physical health, mental health and activity limitation. Descriptive statistics were used to assess sample characteristics. Bivariate and multivariate logistic regression models were used to examine factors associated with the four HRQoL domains. All analyses were stratified by asthma control status. Appropriate survey weights were used to account for the complex survey design. RESULTS: The final sample consisted of 5857 (Weighted: 4 million) late midlife asthmatics, mostly female (66%) and White (72%). About 42% had fair/poor self-rated health, 33% had impaired physical health, 23% had impaired mental health, and 24% experienced activity limitation. Multivariate analyses found that Non-Hispanic African American adults were significantly more likely to report fair/poor self-rated health compared to Whites (Well-controlled asthma OR: 2.2, 95% CI: 1.2-4.1). Adults who experienced any cost barrier were significantly more likely to have activity limitations (Poorly controlled asthma OR: 1.6, 95% CI: 1.1-2.3). Adults with a respiratory comorbidity were more likely to report impaired physical health compared to adults without (Well controlled asthma OR: 1.7, 95% CI: 1.01-2.7). CONCLUSION: Reducing respiratory comorbidities and cost barriers may improve HRQoL in asthmatic late midlife adults.
Authors: Sabina Stanescu; Sarah E Kirby; Mike Thomas; Lucy Yardley; Ben Ainsworth Journal: NPJ Prim Care Respir Med Date: 2019-10-21 Impact factor: 2.871
Authors: Justice Moses K Aheto; Emilia A Udofia; Eugene Kallson; George Mensah; Minicuci Nadia; Naidoo Nirmala; Somnath Chatterji; Paul Kowal; Richard Biritwum; Alfred E Yawson Journal: PLoS One Date: 2020-12-09 Impact factor: 3.240
Authors: Matthias V Kopp; Cathleen Muche-Borowski; Michael Abou-Dakn; Birgit Ahrens; Kirsten Beyer; Katharina Blümchen; Petra Bubel; Adam Chaker; Monika Cremer; Regina Ensenauer; Michael Gerstlauer; Uwe Gieler; Inga-Marie Hübner; Fritz Horak; Ludger Klimek; Berthold V Koletzko; Sybille Koletzko; Susanne Lau; Thomas Lob-Corzilius; Katja Nemat; Eva M J Peters; Antonio Pizzulli; Imke Reese; Claudia Rolinck-Werninghaus; Elien Rouw; Bianca Schaub; Sebastian Schmidt; Jens-Oliver Steiß; Anne Kathrin Striegel; Zsolt Szépfalusi; Dietmar Schlembach; Thomas Spindler; Christian Taube; Valérie Trendelenburg; Regina Treudler; Ulrich Umpfenbach; Christian Vogelberg; Martin Wagenmann; Anke Weißenborn; Thomas Werfel; Margitta Worm; Helmut Sitter; Eckard Hamelmann Journal: Allergol Select Date: 2022-03-04