Literature DB >> 29555207

The Force Is Strong with This One: Metabolism (Over)powers Stem Cell Fate.

Peng Wei1, Katja K Dove1, Claire Bensard1, John C Schell1, Jared Rutter2.   

Abstract

Compared to their differentiated progeny, stem cells are often characterized by distinct metabolic landscapes that emphasize anaerobic glycolysis and a lower fraction of mitochondrial carbohydrate oxidation. Until recently, the metabolic program of stem cells had been thought to be a byproduct of the environment, rather than an intrinsic feature determined by the cell itself. However, new studies highlight the impact of metabolic behavior on the maintenance and function of intestinal stem cells and hair follicle stem cells. This Review summarizes and discusses the evidence that metabolism is not a mere consequence of, but rather influential on stem cell fate.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  fatty acid oxidation; glycolysis; hair follicle stem cells; intestinal stem cells; pyruvate oxidation; stemness

Mesh：

Year:  2018        PMID： 29555207      PMCID： PMC6005741          DOI： 10.1016/j.tcb.2018.02.007

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  38 in total

1.  Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction.

Authors:  Jichun Chen; Clinton M Astle; David E Harrison
Journal:  Exp Hematol       Date:  2003-11       Impact factor: 3.084

2.  Interplay between metabolic identities in the intestinal crypt supports stem cell function.

Authors:  Maria J Rodríguez-Colman; Matthias Schewe; Maaike Meerlo; Edwin Stigter; Johan Gerrits; Mia Pras-Raves; Andrea Sacchetti; Marten Hornsveld; Koen C Oost; Hugo J Snippert; Nanda Verhoeven-Duif; Riccardo Fodde; Boudewijn M T Burgering
Journal:  Nature       Date:  2017-03-08       Impact factor: 49.962

3.  Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.

Authors:  Keiyo Takubo; Go Nagamatsu; Chiharu I Kobayashi; Ayako Nakamura-Ishizu; Hiroshi Kobayashi; Eiji Ikeda; Nobuhito Goda; Yasmeen Rahimi; Randall S Johnson; Tomoyoshi Soga; Atsushi Hirao; Makoto Suematsu; Toshio Suda
Journal:  Cell Stem Cell       Date:  2013-01-03       Impact factor: 24.633

4.  A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth.

Authors:  John C Schell; Kristofor A Olson; Lei Jiang; Amy J Hawkins; Jonathan G Van Vranken; Jianxin Xie; Robert A Egnatchik; Espen G Earl; Ralph J DeBerardinis; Jared Rutter
Journal:  Mol Cell       Date:  2014-10-21       Impact factor: 17.970

5.  The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

Authors:  Tugba Simsek; Fatih Kocabas; Junke Zheng; Ralph J Deberardinis; Ahmed I Mahmoud; Eric N Olson; Jay W Schneider; Cheng Cheng Zhang; Hesham A Sadek
Journal:  Cell Stem Cell       Date:  2010-09-03       Impact factor: 24.633

6.  Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice.

Authors:  Luca Bondolfi; Florian Ermini; Jefferey M Long; Donald K Ingram; Mathias Jucker
Journal:  Neurobiol Aging       Date:  2004-03       Impact factor: 4.673

Review 7.  Wnt signaling in adult intestinal stem cells and cancer.

Authors:  Michaela Krausova; Vladimir Korinek
Journal:  Cell Signal       Date:  2013-12-02       Impact factor: 4.315

8.  Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH.

Authors:  Chiara Stringari; Robert A Edwards; Kira T Pate; Marian L Waterman; Peter J Donovan; Enrico Gratton
Journal:  Sci Rep       Date:  2012-08-10       Impact factor: 4.379

Review 9.  Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP.

Authors:  Jarmon G Lees; David K Gardner; Alexandra J Harvey
Journal:  Stem Cells Int       Date:  2017-07-19       Impact factor: 5.443

10.  A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity.

Authors:  Marlen Knobloch; Gregor-Alexander Pilz; Bart Ghesquière; Werner J Kovacs; Thomas Wegleiter; Darcie L Moore; Martina Hruzova; Nicola Zamboni; Peter Carmeliet; Sebastian Jessberger
Journal:  Cell Rep       Date:  2017-08-29       Impact factor: 9.423
View more
  13 in total

1.  PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism.

Authors:  Rachel R Stine; Alexander P Sakers; Tara TeSlaa; Megan Kissig; Zachary E Stine; Chan Wook Kwon; Lan Cheng; Hee-Woong Lim; Klaus H Kaestner; Joshua D Rabinowitz; Patrick Seale
Journal:  Cell Stem Cell       Date:  2019-09-26       Impact factor: 24.633

Review 2.  Taking the road less traveled - the therapeutic potential of CBP/β-catenin antagonists.

Authors:  Michael Kahn
Journal:  Expert Opin Ther Targets       Date:  2021-10-27       Impact factor: 6.902

3.  A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration.

Authors:  Ana S Brandão; Jorge Borbinha; Telmo Pereira; Patrícia H Brito; Raquel Lourenço; Anabela Bensimon-Brito; Antonio Jacinto
Journal:  Elife       Date:  2022-08-22       Impact factor: 8.713

Review 4.  The Rise of Physiologic Media.

Authors:  Jason R Cantor
Journal:  Trends Cell Biol       Date:  2019-10-14       Impact factor: 20.808

5.  Colorectal Cancer and Metabolism.

Authors:  Rachel E Brown; Sarah P Short; Christopher S Williams
Journal:  Curr Colorectal Cancer Rep       Date:  2018-11-16

6.  Effect of fibronectin, FGF-2, and BMP4 in the stemness maintenance of BMSCs and the metabolic and proteomic cues involved.

Authors:  Lingling Chen; Morgan Carlton; Xiaodan Chen; Navdeep Kaur; Hollie Ryan; Tony J Parker; Zhengmei Lin; Yin Xiao; Yinghong Zhou
Journal:  Stem Cell Res Ther       Date:  2021-03-06       Impact factor: 6.832

7.  Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation.

Authors:  Nadia Badolati; Eduardo Sommella; Gennaro Riccio; Emanuela Salviati; Dimitri Heintz; Sara Bottone; Emery Di Cicco; Monica Dentice; Giancarlo Tenore; Pietro Campiglia; Mariano Stornaiuolo; Ettore Novellino
Journal:  Nutrients       Date:  2018-10-02       Impact factor: 5.717

Review 8.  Quiescence Entry, Maintenance, and Exit in Adult Stem Cells.

Authors:  Karamat Mohammad; Paméla Dakik; Younes Medkour; Darya Mitrofanova; Vladimir I Titorenko
Journal:  Int J Mol Sci       Date:  2019-05-01       Impact factor: 5.923

9.  HNF4 Regulates Fatty Acid Oxidation and Is Required for Renewal of Intestinal Stem Cells in Mice.

Authors:  Lei Chen; Roshan P Vasoya; Natalie H Toke; Aditya Parthasarathy; Shirley Luo; Eric Chiles; Juan Flores; Nan Gao; Edward M Bonder; Xiaoyang Su; Michael P Verzi
Journal:  Gastroenterology       Date:  2019-11-22       Impact factor: 22.682

Review 10.  Understanding the "SMART" features of hematopoietic stem cells and beyond.

Authors:  Shiru Yuan; Guohuan Sun; Yawen Zhang; Fang Dong; Hui Cheng; Tao Cheng
Journal:  Sci China Life Sci       Date:  2021-07-30       Impact factor: 6.038
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.