Yaqoot Fatima1, Suhail A R Doi2, Abdullah Al Mamun3. 1. School of Pharmacy, University of Queensland, Brisbane, Queensland, Australia; Mount Isa Centre for Rural and Remote Health, James Cook University, Queensland, Australia. 2. College of Medicine, Qatar University, Doha, Qatar. 3. Institute for Social Science Research, University of Queensland, Brisbane, Queensland, Australia. Electronic address: yaqoot.fatima@jcu.edu.au.
Abstract
OBJECTIVE: This study aims to explore if there is a causal association between adolescence sleep problems and overweight/obesity (Ow/Ob) in young adults. METHODS: Youth self-reports were used to explore if adolescence (mean age 13.90 years, SD ±0.32) sleep problems lead to general Ow/Ob, computed from body mass index (n = 1075), or abdominal Ow/Ob, computed from waist circumference and waist to height ratio (n = 1179), in young adults (mean age 20.65 years, SD±0.82). Directed acyclic graphs were used to identify potential confounders, modified Poisson regression with a robust error variance was used to model the associations, and inverse probability weights were used to account for loss to follow-up. RESULTS: At adolescence, 27.37% of the subjects reported having frequent sleep problems, and about a fifth of these subjects (22.65%) developed general Ow/Ob at young adulthood. Unadjusted regression analysis indicates a link between adolescent sleep problems and general Ow/Ob in young adults (incidence rate ratio [IRR]: 1.34, 95% confidence interval [CI]: 1.08-2.03), and this link was robust to adjustment for potential confounders (IRR: 1.47, 95% CI: 1.07-2.02). However, no such association was seen for adolescence sleep problems, and abdominal Ow/Ob computed from waist circumference (IRR: 1.30, 95% CI: 0.91-1.87) and waist to height ratio (IRR: 1.27, 95% CI: 0.86-1.88). CONCLUSION: Although there is evidence for a causal association between sleep problems and general Ow/Ob, the link between sleep problems and abdominal Ow/Ob needs more research to produce conclusive results. Nonetheless, behavioral interventions encouraging healthy sleep practice in young subjects are likely to influence future Ow/Ob outcome.
OBJECTIVE: This study aims to explore if there is a causal association between adolescence sleep problems and overweight/obesity (Ow/Ob) in young adults. METHODS: Youth self-reports were used to explore if adolescence (mean age 13.90 years, SD ±0.32) sleep problems lead to general Ow/Ob, computed from body mass index (n = 1075), or abdominal Ow/Ob, computed from waist circumference and waist to height ratio (n = 1179), in young adults (mean age 20.65 years, SD±0.82). Directed acyclic graphs were used to identify potential confounders, modified Poisson regression with a robust error variance was used to model the associations, and inverse probability weights were used to account for loss to follow-up. RESULTS: At adolescence, 27.37% of the subjects reported having frequent sleep problems, and about a fifth of these subjects (22.65%) developed general Ow/Ob at young adulthood. Unadjusted regression analysis indicates a link between adolescent sleep problems and general Ow/Ob in young adults (incidence rate ratio [IRR]: 1.34, 95% confidence interval [CI]: 1.08-2.03), and this link was robust to adjustment for potential confounders (IRR: 1.47, 95% CI: 1.07-2.02). However, no such association was seen for adolescence sleep problems, and abdominal Ow/Ob computed from waist circumference (IRR: 1.30, 95% CI: 0.91-1.87) and waist to height ratio (IRR: 1.27, 95% CI: 0.86-1.88). CONCLUSION: Although there is evidence for a causal association between sleep problems and general Ow/Ob, the link between sleep problems and abdominal Ow/Ob needs more research to produce conclusive results. Nonetheless, behavioral interventions encouraging healthy sleep practice in young subjects are likely to influence future Ow/Ob outcome.
Authors: Guangdong Liu; Shanshan Yang; Wei Liu; Shengshu Wang; Penggang Tai; Fuyin Kou; Wangping Jia; Ke Han; Miao Liu; Yao He Journal: Front Public Health Date: 2020-11-20
Authors: Anna Brzecka; Karolina Sarul; Tomasz Dyła; Marco Avila-Rodriguez; Ricardo Cabezas-Perez; Vladimir N Chubarev; Nina N Minyaeva; Sergey G Klochkov; Margarita E Neganova; Liudmila M Mikhaleva; Siva G Somasundaram; Cecil E Kirkland; Vadim V Tarasov; Gjumrakch Aliev Journal: Curr Genomics Date: 2020-09 Impact factor: 2.236