BACKGROUND AND OBJECTIVE: To evaluate structural changes in the choroid of patients with retinitis pigmentosa (RP) using swept-source optical coherence tomography (OCT) scans. PATIENTS AND METHODS: A prospective study was conducted comparing 35 eyes of 35 patients with RP and 26 eyes of 26 normal patients. OCT images of the choroid were binarized into luminal and stromal areas to derive choroidal vascularity index (CVI). Subfoveal choroidal thickness (CT) was also measured and compared. RESULTS: There was a significant decrease in the mean CVI among eyes with RP as compared to normal eyes (56.91 ± 1.43% vs. 59.47 ± 1.55%; P < .0001). Mean subfoveal CT was significantly greater in eyes with RP as compared to normal eyes (262.82 μm ± 69.69 μm vs. 194.65 μm ± 23.55 μm; P < .0001). CONCLUSION: Patients with RP showed a significant reduction in CVI and an increase in CT as compared to normal eyes. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:191-197.]. Copyright 2018, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To evaluate structural changes in the choroid of patients with retinitis pigmentosa (RP) using swept-source optical coherence tomography (OCT) scans. PATIENTS AND METHODS: A prospective study was conducted comparing 35 eyes of 35 patients with RP and 26 eyes of 26 normal patients. OCT images of the choroid were binarized into luminal and stromal areas to derive choroidal vascularity index (CVI). Subfoveal choroidal thickness (CT) was also measured and compared. RESULTS: There was a significant decrease in the mean CVI among eyes with RP as compared to normal eyes (56.91 ± 1.43% vs. 59.47 ± 1.55%; P < .0001). Mean subfoveal CT was significantly greater in eyes with RP as compared to normal eyes (262.82 μm ± 69.69 μm vs. 194.65 μm ± 23.55 μm; P < .0001). CONCLUSION:Patients with RP showed a significant reduction in CVI and an increase in CT as compared to normal eyes. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:191-197.]. Copyright 2018, SLACK Incorporated.
Authors: Hao Zhou; Yining Dai; Yingying Shi; Jonathan F Russell; Cancan Lyu; Jila Noorikolouri; William J Feuer; Zhongdi Chu; Qinqin Zhang; Luis de Sisternes; Mary K Durbin; Giovanni Gregori; Philip J Rosenfeld; Ruikang K Wang Journal: Ophthalmol Retina Date: 2019-10-01
Authors: Hao Zhou; Jie Lu; Kelly Chen; Yingying Shi; Giovanni Gregori; Philip J Rosenfeld; Ruikang K Wang Journal: Quant Imaging Med Surg Date: 2022-05
Authors: Li Su; Wongsiri Taweebanjongsin; Stephanie L Gaw; Gilad Rabina; SriniVas R Sadda; Irena Tsui Journal: Transl Vis Sci Technol Date: 2020-08-13 Impact factor: 3.283