Amit Meshi1, Tiezhu Lin1,2, Kunny Dans1, Kevin C Chen1, Manuel Amador1,3, Kyle Hasenstab4, Ilkay Kilic Muftuoglu1,5, Eric Nudleman6, Daniel Chao6, Dirk-Uwe Bartsch1, William R Freeman1. 1. Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California San Diego, La Jolla, California. 2. He Eye Hospital, He University, Shenyang, China. 3. Escuela Superior de Oftalmologia, Instituto Barraquer de America, Bogota, Colombia. 4. Department of Ophthalmology, Hamilton Glaucoma Center at Shiley Eye Institute, University of California San Diego, La Jolla, California. 5. Department of Ophthalmology, Istanbul Training and Research Hospital, Istanbul, Turkey. 6. Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California.
Abstract
PURPOSE: To compare retinal pathology visualization in multispectral scanning laser ophthalmoscope imaging between the Spectralis and Optos devices. METHODS: This retrospective cross-sectional study included 42 eyes from 30 patients with age-related macular degeneration (19 eyes), diabetic retinopathy (10 eyes), and epiretinal membrane (13 eyes). All patients underwent retinal imaging with a color fundus camera (broad-spectrum white light), the Spectralis HRA-2 system (3-color monochromatic lasers), and the Optos P200 system (2-color monochromatic lasers). The Optos image was cropped to a similar size as the Spectralis image. Seven masked graders marked retinal pathologies in each image within a 5 × 5 grid that included the macula. RESULTS: The average area with detected retinal pathology in all eyes was larger in the Spectralis images compared with Optos images (32.4% larger, P < 0.0001), mainly because of better visualization of epiretinal membrane and retinal hemorrhage. The average detection rate of age-related macular degeneration and diabetic retinopathy pathologies was similar across the three modalities, whereas epiretinal membrane detection rate was significantly higher in the Spectralis images. CONCLUSION: Spectralis tricolor multispectral scanning laser ophthalmoscope imaging had higher rate of pathology detection primarily because of better epiretinal membrane and retinal hemorrhage visualization compared with Optos bicolor multispectral scanning laser ophthalmoscope imaging.
PURPOSE: To compare retinal pathology visualization in multispectral scanning laser ophthalmoscope imaging between the Spectralis and Optos devices. METHODS: This retrospective cross-sectional study included 42 eyes from 30 patients with age-related macular degeneration (19 eyes), diabetic retinopathy (10 eyes), and epiretinal membrane (13 eyes). All patients underwent retinal imaging with a color fundus camera (broad-spectrum white light), the Spectralis HRA-2 system (3-color monochromatic lasers), and the Optos P200 system (2-color monochromatic lasers). The Optos image was cropped to a similar size as the Spectralis image. Seven masked graders marked retinal pathologies in each image within a 5 × 5 grid that included the macula. RESULTS: The average area with detected retinal pathology in all eyes was larger in the Spectralis images compared with Optos images (32.4% larger, P < 0.0001), mainly because of better visualization of epiretinal membrane and retinal hemorrhage. The average detection rate of age-related macular degeneration and diabetic retinopathy pathologies was similar across the three modalities, whereas epiretinal membrane detection rate was significantly higher in the Spectralis images. CONCLUSION:Spectralis tricolor multispectral scanning laser ophthalmoscope imaging had higher rate of pathology detection primarily because of better epiretinal membrane and retinal hemorrhage visualization compared with Optos bicolor multispectral scanning laser ophthalmoscope imaging.
Authors: Mark P Espina; Cheryl A Arcinue; Feiyan Ma; Natalia Camacho; Dirk-Uwe G Bartsch; William R Freeman Journal: Retina Date: 2015-12 Impact factor: 4.256
Authors: Martin A Mainster; Thomas Desmettre; Giuseppe Querques; Patricia L Turner; Gerardo Ledesma-Gil Journal: Int J Retina Vitreous Date: 2022-09-30