| Literature DB >> 29553810 |
Weiyang Liu1, Senhua Chen2, Jing Li1, Xuemei Yang1, Chong Yan1, Hongju Liu1.
Abstract
A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2-6) were isolated from a fungus Colletotrichum sp . GDMU-1 derived from the leaves of Santalum album. Their structures were determined by detailed analysis of spectroscopic data. All compounds were tested for the inhibitory effects on the nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW264.7 cells. Among them, compounds 4 and 5 showed moderate anti-inflammatory activity with IC50 value of 30.4 and 8.9 μM, respectively.Entities:
Keywords: sp; -tetralonyl glucoside; anti-inflammatory activity
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Year: 2018 PMID： 29553810 DOI： 10.1080/14786419.2018.1452003
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861