Literature DB >> 29548516

Neuronal Fat and Dendrite Morphogenesis: The Goldilocks Effect.

Lakshmi Sundararajan1, David M Miller2.   

Abstract

Two recent studies by Meltzer et al. and Ziegler et al. use Drosophila larvae to demonstrate that cell-autonomous regulation of lipid biosynthesis defines the complexity and function of highly branched nociceptive neurons. Their findings show that lipid biosynthesis in the neuron is fine-tuned for optimal dendrite morphology and sensitivity.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Drosophila da neuron; dendrite morphogenesis; lipid biosynthesis; nociceptive sensory neuron

Mesh：

Substances：

Year:  2018        PMID： 29548516      PMCID： PMC5924613          DOI： 10.1016/j.tins.2018.02.011

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  10 in total

1.  Critical time window of neuronal cholesterol synthesis during neurite outgrowth.

Authors:  Ursula Fünfschilling; Wolf J Jockusch; Nandhini Sivakumar; Wiebke Möbius; Kristina Corthals; Sai Li; Susanne Quintes; Younghoon Kim; Iwan A T Schaap; Jeong-Seop Rhee; Klaus-Armin Nave; Gesine Saher
Journal:  J Neurosci       Date:  2012-05-30       Impact factor: 6.167

2.  Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila.

Authors:  I Y Dobrosotskaya; A C Seegmiller; M S Brown; J L Goldstein; R B Rawson
Journal:  Science       Date:  2002-05-03       Impact factor: 47.728

3.  Phospholipids that contain polyunsaturated fatty acids enhance neuronal cell mechanics and touch sensation.

Authors:  Valeria Vásquez; Michael Krieg; Dean Lockhead; Miriam B Goodman
Journal:  Cell Rep       Date:  2014-01-02       Impact factor: 9.423

4.  Lipid composition of the normal human brain: gray matter, white matter, and myelin.

Authors:  J S O'Brien; E L Sampson
Journal:  J Lipid Res       Date:  1965-10       Impact factor: 5.922

5.  Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons.

Authors:  Shan Meltzer; Joshua A Bagley; Gerardo Lopez Perez; Caitlin E O'Brien; Laura DeVault; Yanmeng Guo; Lily Yeh Jan; Yuh-Nung Jan
Journal:  Cell Rep       Date:  2017-10-24       Impact factor: 9.423

6.  Cell-Autonomous Control of Neuronal Dendrite Expansion via the Fatty Acid Synthesis Regulator SREBP.

Authors:  Anna B Ziegler; Christoph Thiele; Federico Tenedini; Mélisande Richard; Philipp Leyendecker; Astrid Hoermann; Peter Soba; Gaia Tavosanis
Journal:  Cell Rep       Date:  2017-12-19       Impact factor: 9.423

Review 7.  Branching out: mechanisms of dendritic arborization.

Authors:  Yuh-Nung Jan; Lily Yeh Jan
Journal:  Nat Rev Neurosci       Date:  2010-05       Impact factor: 34.870

Review 8.  SREBPs: SREBP function in glia-neuron interactions.

Authors:  Nutabi Camargo; August B Smit; Mark H G Verheijen
Journal:  FEBS J       Date:  2009-02       Impact factor: 5.542

9.  Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis.

Authors:  Marlen Knobloch; Simon M G Braun; Luis Zurkirchen; Carolin von Schoultz; Nicola Zamboni; Marcos J Araúzo-Bravo; Werner J Kovacs; Ozlem Karalay; Ueli Suter; Raquel A C Machado; Marta Roccio; Matthias P Lutolf; Clay F Semenkovich; Sebastian Jessberger
Journal:  Nature       Date:  2012-12-02       Impact factor: 49.962

10.  The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis.

Authors:  P Pavlidis; M Ramaswami; M A Tanouye
Journal:  Cell       Date:  1994-10-07       Impact factor: 41.582
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.