Literature DB >> 29546683

Antidiabetic effects of novel cell culture established from grapevine, Vitis vinifera cv. Koshu.

Keiko Fujita1, Yoshinao Aoki2, Shunji Suzuki3.   

Abstract

Vitis vinifera cv. Koshu is an indigenous cultivar in Japan and has several characteristics that distinguish it from European V. vinifera. In Japan, Koshu is the most popular cultivar for wine making. We report herein a cell culture established from Koshu for use as a system for the production of resveratrol and its derivatives. Grape cell culture YU-1 was developed from the apex tissues of Koshu. YU-1 growth was favorably compared with BY-2 growth, a standard cell line in plant cell biology. Stilbene production and stilbene synthesis gene expression in YU-1 were upregulated by UV-C irradiation. YU-1 irradiated with UV-C decreased hemolymph sugar levels in model animals. Taken together, this study suggests that YU-1 may be used as a source of valuable medicinal components in plant cell bioreactor systems.

Entities:  

Keywords:  Antidiabetic; Hypoglycemic effect; Koshu; Resveratrol; Vitis vinifera

Year:  2018        PMID： 29546683      PMCID： PMC6021287          DOI： 10.1007/s10616-018-0203-y

Source DB:  PubMed          Journal:  Cytotechnology        ISSN： 0920-9069            Impact factor:   2.058


  12 in total

1.  Effects of elicitors on the production of resveratrol and viniferins in cell cultures of Vitis vinifera L. cv Italia.

Authors:  Anna Rita Santamaria; Nadia Mulinacci; Alessio Valletta; Marzia Innocenti; Gabriella Pasqua
Journal:  J Agric Food Chem       Date:  2011-08-12       Impact factor: 5.279

2.  Condensed tannin and anthocyanin production in Vitis vinifera cell suspension cultures.

Authors:  A Decendit; J M Mérillon
Journal:  Plant Cell Rep       Date:  1996-06       Impact factor: 4.570

3.  Enhanced extracellular production of trans-resveratrol in Vitis vinifera suspension cultured cells by using cyclodextrins and methyljasmonate.

Authors:  Sarai Belchí-Navarro; Lorena Almagro; Diego Lijavetzky; Roque Bru; María A Pedreño
Journal:  Plant Cell Rep       Date:  2011-09-07       Impact factor: 4.570

Review 4.  Anti-diabetic effects of resveratrol.

Authors:  Tomasz Szkudelski; Katarzyna Szkudelska
Journal:  Ann N Y Acad Sci       Date:  2011-01       Impact factor: 5.691

5.  Grapevine cell early activation of specific responses to DIMEB, a resveratrol elicitor.

Authors:  Anita Zamboni; Pamela Gatto; Alessandro Cestaro; Stefania Pilati; Roberto Viola; Fulvio Mattivi; Claudio Moser; Riccardo Velasco
Journal:  BMC Genomics       Date:  2009-08-06       Impact factor: 3.969

Review 6.  Resveratrol as a calorie restriction mimetic: therapeutic implications.

Authors:  Jay H Chung; Vincent Manganiello; Jason R B Dyck
Journal:  Trends Cell Biol       Date:  2012-08-10       Impact factor: 20.808

7.  An invertebrate hyperglycemic model for the identification of anti-diabetic drugs.

Authors:  Yasuhiko Matsumoto; Eriko Sumiya; Takuya Sugita; Kazuhisa Sekimizu
Journal:  PLoS One       Date:  2011-03-30       Impact factor: 3.240

8.  Pink-colored grape berry is the result of short insertion in intron of color regulatory gene.

Authors:  Mamiko Shimazaki; Keiko Fujita; Hironori Kobayashi; Shunji Suzuki
Journal:  PLoS One       Date:  2011-06-17       Impact factor: 3.240

Review 9.  Role of red grape polyphenols as antidiabetic agents.

Authors:  Kanti Bhooshan Pandey; Syed Ibrahim Rizvi
Journal:  Integr Med Res       Date:  2014-07-15

10.  Anti-Cancer Activity of Resveratrol and Derivatives Produced by Grapevine Cell Suspensions in a 14 L Stirred Bioreactor.

Authors:  Laetitia Nivelle; Jane Hubert; Eric Courot; Philippe Jeandet; Aziz Aziz; Jean-Marc Nuzillard; Jean-Hugues Renault; Christophe Clément; Laurent Martiny; Dominique Delmas; Michel Tarpin
Journal:  Molecules       Date:  2017-03-16       Impact factor: 4.411
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  2 in total

1.  Crosstalk Pathway between Trehalose Metabolism and Cytokinin Degradation for the Determination of the Number of Berries per Bunch in Grapes.

Authors:  Ayane Moriyama; Chiho Yamaguchi; Shinichi Enoki; Yoshinao Aoki; Shunji Suzuki
Journal:  Cells       Date:  2020-10-29       Impact factor: 6.600

2.  Antiviral Activity of Vitis vinifera Leaf Extract against SARS-CoV-2 and HSV-1.

Authors:  Carla Zannella; Rosa Giugliano; Annalisa Chianese; Carmine Buonocore; Giovanni Andrea Vitale; Giuseppina Sanna; Federica Sarno; Aldo Manzin; Angela Nebbioso; Pasquale Termolino; Lucia Altucci; Massimiliano Galdiero; Donatella de Pascale; Gianluigi Franci
Journal:  Viruses       Date:  2021-06-29       Impact factor: 5.048
  2 in total

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