Literature DB >> 29545670

Burosumab: A new drug to treat hypophosphatemic rickets.

Stepan Kutilek1,2,3.   

Abstract

Burosumab (KRN23) is a fully human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets. A report enclosed in this letter gives a brief review of current knowledge on burosumab therapy.

Entities:  

Keywords:  Burosumab; Hypophosphatemic rickets; KRN23.

Year:  2017        PMID： 29545670      PMCID： PMC5845463          DOI： 10.24911/SJP.2017.2.11

Source DB:  PubMed          Journal:  Sudan J Paediatr        ISSN： 0256-4408


  3 in total

1.  X-linked hypophosphatemic rickets (PHEX mutation): A case report and literature review.

Authors:  Badi Alenazi; M A Maleque Molla; Abdullah Alshaya; Mahmoud Saleh
Journal:  Sudan J Paediatr       Date:  2017

2.  Prolonged Correction of Serum Phosphorus in Adults With X-Linked Hypophosphatemia Using Monthly Doses of KRN23.

Authors:  Erik A Imel; Xiaoping Zhang; Mary D Ruppe; Thomas J Weber; Mark A Klausner; Takahiro Ito; Maria Vergeire; Jeffrey S Humphrey; Francis H Glorieux; Anthony A Portale; Karl Insogna; Munro Peacock; Thomas O Carpenter
Journal:  J Clin Endocrinol Metab       Date:  2015-04-28       Impact factor: 5.958

3.  Effect of four monthly doses of a human monoclonal anti-FGF23 antibody (KRN23) on quality of life in X-linked hypophosphatemia.

Authors:  Mary D Ruppe; Xiaoping Zhang; Erik A Imel; Thomas J Weber; Mark A Klausner; Takahiro Ito; Maria Vergeire; Jeffrey S Humphrey; Francis H Glorieux; Anthony A Portale; Karl Insogna; Munro Peacock; Thomas O Carpenter
Journal:  Bone Rep       Date:  2016-05-13
  3 in total
  1 in total

1.  PHEX Gene Mutation in a Patient with X-Linked Hypophosphatemic Rickets in a Developing Country.

Authors:  Jessica María Forero-Delgadillo; Daniela Cleves; Vanessa Ochoa; Hernando Londoño-Correa; Jaime Manuel Restrepo; José Antonio Nastasi-Catanese; Harry Pachajoa
Journal:  Appl Clin Genet       Date:  2020-02-13
  1 in total

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