Literature DB >> 29545550

Cancer: Tipping the splicing balance to kill cancer cells.

Megan Cully.   

Abstract

Entities:  

Year:  2018        PMID: 29545550     DOI: 10.1038/nrd.2018.38

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  1 in total

1.  H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers.

Authors:  Michael Seiler; Akihide Yoshimi; Rachel Darman; Betty Chan; Gregg Keaney; Michael Thomas; Anant A Agrawal; Benjamin Caleb; Alfredo Csibi; Eckley Sean; Peter Fekkes; Craig Karr; Virginia Klimek; George Lai; Linda Lee; Pavan Kumar; Stanley Chun-Wei Lee; Xiang Liu; Crystal Mackenzie; Carol Meeske; Yoshiharu Mizui; Eric Padron; Eunice Park; Ermira Pazolli; Shouyong Peng; Sudeep Prajapati; Justin Taylor; Teng Teng; John Wang; Markus Warmuth; Huilan Yao; Lihua Yu; Ping Zhu; Omar Abdel-Wahab; Peter G Smith; Silvia Buonamici
Journal:  Nat Med       Date:  2018-02-19       Impact factor: 53.440

  1 in total

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