Michael L O'Byrne1,2,3,4, Michael G McBride1,2, Stephen Paridon1,2, Elizabeth Goldmuntz1,2. 1. 1 Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. 2. 2 Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. 3. 3 Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, USA. 4. 4 Leonard Davis Institute, University of Pennsylvania, Philadelphia, PA, USA.
Abstract
BACKGROUND: Obesity is associated with increased lifelong morbidity and reduced life span and is increasingly prevalent in the congenital heart disease population. Habitual exercise is an important aspect of a healthy lifestyle and primary prevention of obesity in the general population. The association between habitual activity and body mass index (BMI) has not been studied in children with congenital heart disease. METHODS: A cross-sectional analysis of two previously collected cohorts was performed, including participants 8 to 18 years old with tetralogy of Fallot, transposition of the great arteries, and single ventricle heart disease after a Fontan operation. The association between BMI and duration of habitual exercise (measured by questionnaire) was studied. Secondary analyses assessing the effect of other possible factors for BMI were performed. RESULTS: In total, 172 participants were studied (45% Tetralogy of Fallot, 12% transposition of the great arteries, and 43% Fontan). Median BMI was 18.2, and 29% of the participants were obese or overweight. Median habitual exercise was 5.9 h/wk. Thirty-eight percent of participants reported having their activity restricted by their cardiologist. Increasing exercise duration was associated with lower BMI ( P = .01) in univariate analysis. In secondary analyses, restriction to mild exertion and participation in low-intensity exercise were both associated with increased BMI. CONCLUSION: Increased habitual activity was associated with lower BMI, emphasizing the potential role of recreational sport in the health of children with congenital heart disease.
BACKGROUND:Obesity is associated with increased lifelong morbidity and reduced life span and is increasingly prevalent in the congenital heart disease population. Habitual exercise is an important aspect of a healthy lifestyle and primary prevention of obesity in the general population. The association between habitual activity and body mass index (BMI) has not been studied in children with congenital heart disease. METHODS: A cross-sectional analysis of two previously collected cohorts was performed, including participants 8 to 18 years old with tetralogy of Fallot, transposition of the great arteries, and single ventricle heart disease after a Fontan operation. The association between BMI and duration of habitual exercise (measured by questionnaire) was studied. Secondary analyses assessing the effect of other possible factors for BMI were performed. RESULTS: In total, 172 participants were studied (45% Tetralogy of Fallot, 12% transposition of the great arteries, and 43% Fontan). Median BMI was 18.2, and 29% of the participants were obese or overweight. Median habitual exercise was 5.9 h/wk. Thirty-eight percent of participants reported having their activity restricted by their cardiologist. Increasing exercise duration was associated with lower BMI ( P = .01) in univariate analysis. In secondary analyses, restriction to mild exertion and participation in low-intensity exercise were both associated with increased BMI. CONCLUSION: Increased habitual activity was associated with lower BMI, emphasizing the potential role of recreational sport in the health of children with congenital heart disease.
Entities:
Keywords:
exercise physiology; hypoplastic left heart syndrome; outcomes research; pediatric cardiology; transposition of the great arteries
Authors: Michael L O'Byrne; Laura Mercer-Rosa; Eitan Ingall; Michael G McBride; Stephen Paridon; Elizabeth Goldmuntz Journal: Pediatr Cardiol Date: 2012-10-27 Impact factor: 1.655
Authors: Michael L O'Byrne; Laura Mercer-Rosa; Huaqing Zhao; Xuemei Zhang; Wei Yang; Amy Cassedy; Mark A Fogel; Jack Rychik; Ronn E Tanel; Bradley S Marino; Stephen Paridon; Elizabeth Goldmuntz Journal: Am Heart J Date: 2013-07-16 Impact factor: 4.749
Authors: Brian W McCrindle; Richard V Williams; Seema Mital; Bernard J Clark; Jennifer L Russell; Gloria Klein; Joey C Eisenmann Journal: Arch Dis Child Date: 2007-02-16 Impact factor: 3.791
Authors: Yves d'Udekem; Michael M H Cheung; Stella Setyapranata; Ajay J Iyengar; Patricia Kelly; Naomi Buckland; Leeanne E Grigg; Robert G Weintraub; Alasdair Vance; Christian P Brizard; Dan J Penny Journal: Ann Thorac Surg Date: 2009-12 Impact factor: 4.330
Authors: Allison A Hedley; Cynthia L Ogden; Clifford L Johnson; Margaret D Carroll; Lester R Curtin; Katherine M Flegal Journal: JAMA Date: 2004-06-16 Impact factor: 56.272
Authors: Gil Wernovsky; Jonathan J Rome; Sarah Tabbutt; Jack Rychik; Meryl S Cohen; Stephen M Paridon; Gary Webb; Kathryn M Dodds; Maureen A Gallagher; Desiree A Fleck; Thomas L Spray; Victoria L Vetter; Marie M Gleason Journal: Congenit Heart Dis Date: 2006-01 Impact factor: 2.007
Authors: Michael L O'Byrne; Laura Mercer-Rosa; Huaqing Zhao; Xuemei Zhang; Wei Yang; Ronn E Tanel; Bradley S Marino; Amy Cassedy; Mark A Fogel; Jack Rychik; Stephen Paridon; Elizabeth Goldmuntz Journal: Pediatr Cardiol Date: 2013-09-15 Impact factor: 1.655
Authors: Lars Bo Andersen; Maarike Harro; Luis B Sardinha; Karsten Froberg; Ulf Ekelund; Søren Brage; Sigmund Alfred Anderssen Journal: Lancet Date: 2006-07-22 Impact factor: 79.321