Literature DB >> 29544094

A Sleeping Area of Malaria Research Awakes.

Elizabeth A Winzeler1.   

Abstract

Phenotypic screening methods have had a profound impact on antimalarial drug development, but assays that predict which compounds might provide a radical cure have remained elusive. In this issue of Cell Host & Microbe, Gural et al. (2018) report hypnozoite culturing and systems to study these elusive, yet deadly, parasites.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29544094     DOI: 10.1016/j.chom.2018.02.008

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  1 in total

1.  Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine.

Authors:  Erika L Flannery; Niwat Kangwanrangsan; Vorada Chuenchob; Wanlapa Roobsoong; Matthew Fishbaugher; Kevin Zhou; Zachary P Billman; Thomas Martinson; Tayla M Olsen; Carola Schäfer; Brice Campo; Sean C Murphy; Sebastian A Mikolajczak; Stefan H I Kappe; Jetsumon Sattabongkot
Journal:  Mol Ther Methods Clin Dev       Date:  2022-08-02       Impact factor: 5.849

  1 in total

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