Literature DB >> 29537950

Management of Bone Defects in Orthopedic Trauma.

Philip H Locker, Jaymeson Arthur, Tori Edmiston, Rajeev Puri, Brett R Levine.   

Abstract

Treatment of traumatic bone defects is dictated by a multitude of clinical factors including the defect size, patient comorbidities, soft tissue condition, and the possibility of infection present in the defect. With a variety of treatment strategies described, it is critical to choose the approach that will maximize outcomes in addressing this difficult problem. When addressing small-scale defects, bone grafting is the primary treatment. For large-scale defects, there are two major options to consider: induced membrane technique and distraction osteogenesis. Choosing between these two techniques should be based on the associated soft tissue injury, the local vascularity, and the possibility of residual infection. This review will focus on the current management principles and strategies in the treatment of bone defects after orthopedic trauma and the existing literature to support each of these treatment options.

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Year:  2018        PMID: 29537950

Source DB:  PubMed          Journal:  Bull Hosp Jt Dis (2013)        ISSN: 2328-4633


  7 in total

Review 1.  Stem Cell-Laden Hydrogel-Based 3D Bioprinting for Bone and Cartilage Tissue Engineering.

Authors:  Zhimin Yang; Ping Yi; Zhongyue Liu; Wenchao Zhang; Lin Mei; Chengyao Feng; Chao Tu; Zhihong Li
Journal:  Front Bioeng Biotechnol       Date:  2022-05-17

Review 2.  Recent Advances in Enhancement Strategies for Osteogenic Differentiation of Mesenchymal Stem Cells in Bone Tissue Engineering.

Authors:  Kangkang Zha; Yue Tian; Adriana C Panayi; Bobin Mi; Guohui Liu
Journal:  Front Cell Dev Biol       Date:  2022-02-23

3.  TGFβ1 induces bone formation from BMP9-activated Bone Mesenchymal Stem Cells, with possible involvement of non-canonical pathways.

Authors:  Huan Yao; Yulong Zou; Ke Yang; Liangjun Yin; Yang Liu; Ruidong Li
Journal:  Int J Med Sci       Date:  2020-07-02       Impact factor: 3.738

4.  Therapeutic Effects of Revascularisation on the Healing of Free Bone Grafts in Dogs.

Authors:  Jia-San Zheng; Hong-Ri Ruan; Kai-Wen Hou
Journal:  J Vet Res       Date:  2020-03-24       Impact factor: 1.744

5.  Acute-shortening and re-lengthening (ASRL) procedure with monorail fixator to treat femur/tibia nonunion: A retrospective study.

Authors:  Asep Santoso; Hendra Cahya Kumara; Seti Aji Hadinoto; Dimas Prasetyo Adi Prakoso; Mujaddid Idulhaq; Tito Sumarwoto; Ismail Mariyanto
Journal:  Ann Med Surg (Lond)       Date:  2021-07-28

6.  Osteogenesis Improvement of Gelatin-Based Nanocomposite Scaffold by Loading Zoledronic Acid.

Authors:  Sayed Behnam Abdulahy; Mona Esmaeili Bidhendi; Mohammad Reza Vaezi; Mehrdad Moosazadeh Moghaddam
Journal:  Front Bioeng Biotechnol       Date:  2022-04-25

Review 7.  Multi-functional osteoclasts in matrix-based tissue engineering bone.

Authors:  Yue-Qi Chen; Wen-Hui Hu; Zi-Cai Dong; Shi-Wu Dong
Journal:  Chin J Traumatol       Date:  2021-11-26
  7 in total

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