Literature DB >> 29537301

α2-macroglobulin in Alzheimer's disease: new roles for an old chaperone.

Sahba Seddighi1, Vijay Varma1, Madhav Thambisetty1.   

Abstract

Entities:  

Keywords:  Alzheimer's disease; biomarkers; cerebrospinal fluid; chaperone; inflammation; neuroimaging; plasma; α2-macroglobulin

Mesh：

Substances：

Year:  2018        PMID： 29537301      PMCID： PMC5967355          DOI： 10.2217/bmm-2018-0027

Source DB:  PubMed          Journal:  Biomark Med        ISSN： 1752-0363            Impact factor:   2.851


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  36 in total

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Journal:  Ageing Res Rev       Date:  2010-05-02       Impact factor: 10.895

2.  Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.

Authors:  V R Varma; S Varma; Y An; T J Hohman; S Seddighi; R Casanova; A Beri; E B Dammer; N T Seyfried; O Pletnikova; A Moghekar; M R Wilson; J J Lah; R J O'Brien; A I Levey; J C Troncoso; M S Albert; M Thambisetty
Journal:  Mol Psychiatry       Date:  2016-11-22       Impact factor: 15.992

3.  The relative risk and timing of divorce in families of children with an autism spectrum disorder.

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Review 4.  Alpha2-macroglobulin: an evolutionarily conserved arm of the innate immune system.

Authors:  P B Armstrong; J P Quigley
Journal:  Dev Comp Immunol       Date:  1999 Jun-Jul       Impact factor: 3.636

5.  The unfolded protein response is activated in Alzheimer's disease.

Authors:  J J M Hoozemans; R Veerhuis; E S Van Haastert; J M Rozemuller; F Baas; P Eikelenboom; W Scheper
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Review 6.  α2-Macroglobulin: Autologous Protease Inhibition Technology.

Authors:  Jason M Cuéllar; Vanessa Gabrovsky Cuéllar; Gaetano J Scuderi
Journal:  Phys Med Rehabil Clin N Am       Date:  2016-11       Impact factor: 1.784

7.  Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC.

Authors:  Hakan Kucukdereli; Nicola J Allen; Anthony T Lee; Ava Feng; M Ilcim Ozlu; Laura M Conatser; Chandrani Chakraborty; Gail Workman; Matthew Weaver; E Helene Sage; Ben A Barres; Cagla Eroglu
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Review 8.  Amyloid-beta oligomers: possible roles as key neurotoxins in Alzheimer's Disease.

Authors:  Alex L Lublin; Sam Gandy
Journal:  Mt Sinai J Med       Date:  2010 Jan-Feb

Review 9.  Neuroinflammation in Alzheimer's disease.

Authors:  Michael T Heneka; Monica J Carson; Joseph El Khoury; Gary E Landreth; Frederic Brosseron; Douglas L Feinstein; Andreas H Jacobs; Tony Wyss-Coray; Javier Vitorica; Richard M Ransohoff; Karl Herrup; Sally A Frautschy; Bente Finsen; Guy C Brown; Alexei Verkhratsky; Koji Yamanaka; Jari Koistinaho; Eicke Latz; Annett Halle; Gabor C Petzold; Terrence Town; Dave Morgan; Mari L Shinohara; V Hugh Perry; Clive Holmes; Nicolas G Bazan; David J Brooks; Stéphane Hunot; Bertrand Joseph; Nikolaus Deigendesch; Olga Garaschuk; Erik Boddeke; Charles A Dinarello; John C Breitner; Greg M Cole; Douglas T Golenbock; Markus P Kummer
Journal:  Lancet Neurol       Date:  2015-04       Impact factor: 44.182

10.  The role of astrocyte-secreted matricellular proteins in central nervous system development and function.

Authors:  Cagla Eroglu
Journal:  J Cell Commun Signal       Date:  2009-11-11       Impact factor: 5.782
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1.  Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin.

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Journal:  Proc Natl Acad Sci U S A       Date:  2022-05-02       Impact factor: 12.779

2.  Levels of α-2 Macroglobulin in cognitively normal Mexican- Americans with Subjective Cognitive Decline: A HABLE Study.

Authors:  James R Hall; April R Wiechmann; Leigh A Johnson; Melissa L Edwards; Sid E O'Bryant
Journal:  Curr Neurobiol       Date:  2019-04

3.  Network medicine for disease module identification and drug repurposing with the NeDRex platform.

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Journal:  Nat Commun       Date:  2021-11-25       Impact factor: 14.919
  3 in total

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