Literature DB >> 29534981

Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.

Andrew J Lutkewitte1, George G Schweitzer2, Stefanie Kennon-McGill3, Melissa M Clemens4, Laura P James5, Hartmut Jaeschke6, Brian N Finck7, Mitchell R McGill8.   

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Year:  2018        PMID： 29534981      PMCID： PMC5935563          DOI： 10.1016/j.fct.2018.03.014

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN： 0278-6915            Impact factor:   6.023


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  54 in total

1.  Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice.

Authors:  Ming Hu; Fengming Wang; Xin Li; Christopher Q Rogers; Xiaomei Liang; Brian N Finck; Mayurranjan S Mitra; Ray Zhang; Dave A Mitchell; Min You
Journal:  Hepatology       Date:  2011-12-29       Impact factor: 17.425

2.  Rapid mitogenic regulation of the mTORC1 inhibitor, DEPTOR, by phosphatidic acid.

Authors:  Mee-Sup Yoon; Christina L Rosenberger; Cong Wu; Nga Truong; Jonathan V Sweedler; Jie Chen
Journal:  Mol Cell       Date:  2015-04-30       Impact factor: 17.970

3.  Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.

Authors:  Kuo Du; Anup Ramachandran; Mitchell R McGill; Abdellah Mansouri; Tarik Asselah; Anwar Farhood; Benjamin L Woolbright; Wen-Xing Ding; Hartmut Jaeschke
Journal:  Food Chem Toxicol       Date:  2017-08-18       Impact factor: 6.023

4.  Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

Authors:  Jeremiah N Winter; Todd E Fox; Mark Kester; Leonard S Jefferson; Scot R Kimball
Journal:  Am J Physiol Cell Physiol       Date:  2010-04-28       Impact factor: 4.249

Review 5.  Hepatostat: Liver regeneration and normal liver tissue maintenance.

Authors:  George K Michalopoulos
Journal:  Hepatology       Date:  2017-03-06       Impact factor: 17.425

6.  Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.

Authors:  Bharat Bhushan; Hemantkumar Chavan; Prachi Borude; Yuchao Xie; Kuo Du; Mitchell R McGill; Margitta Lebofsky; Hartmut Jaeschke; Partha Krishnamurthy; Udayan Apte
Journal:  Toxicol Sci       Date:  2016-10-23       Impact factor: 4.849

7.  Alpha-fetoprotein is a predictor of outcome in acetaminophen-induced liver injury.

Authors:  Lars E Schmidt; Kim Dalhoff
Journal:  Hepatology       Date:  2005-01       Impact factor: 17.425

8.  Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children.

Authors:  Sudeepa Bhattacharyya; Ke Yan; Lisa Pence; Pippa M Simpson; Pritmohinder Gill; Lynda G Letzig; Richard D Beger; Janice E Sullivan; Gregory L Kearns; Michael D Reed; James D Marshall; John N Van Den Anker; Laura P James
Journal:  Biomark Med       Date:  2014       Impact factor: 2.851

9.  Generation of a mouse expressing a conditional knockout of the hepatocyte growth factor gene: demonstration of impaired liver regeneration.

Authors:  Daniel Phaneuf; A David Moscioni; Cynthia LeClair; Steven E Raper; James M Wilson
Journal:  DNA Cell Biol       Date:  2004-09       Impact factor: 3.311

10.  Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.

Authors:  Wenliang Zhang; Wei Zhong; Qian Sun; Xinguo Sun; Zhanxiang Zhou
Journal:  Sci Rep       Date:  2018-01-11       Impact factor: 4.379
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  13 in total

1.  The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.

Authors:  Melissa M Clemens; Stefanie Kennon-McGill; Udayan Apte; Laura P James; Brian N Finck; Mitchell R McGill
Journal:  Food Chem Toxicol       Date:  2019-01-14       Impact factor: 6.023

Review 2.  Biomarkers of drug-induced liver injury.

Authors:  Mitchell R McGill; Hartmut Jaeschke
Journal:  Adv Pharmacol       Date:  2019-03-06

Review 3.  Animal models of drug-induced liver injury.

Authors:  Mitchell R McGill; Hartmut Jaeschke
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2018-09-03       Impact factor: 5.187

Review 4.  Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction.

Authors:  Antonio Segovia-Zafra; Daniel E Di Zeo-Sánchez; Carlos López-Gómez; Zeus Pérez-Valdés; Eduardo García-Fuentes; Raúl J Andrade; M Isabel Lucena; Marina Villanueva-Paz
Journal:  Acta Pharm Sin B       Date:  2021-11-18       Impact factor: 11.413

Review 5.  Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation.

Authors:  Mitchell R McGill; Hartmut Jaeschke
Journal:  Expert Rev Mol Diagn       Date:  2018-08-13       Impact factor: 5.225

6.  Lack of Multidrug Resistance-associated Protein 4 Prolongs Partial Hepatectomy-induced Hepatic Steatosis.

Authors:  Ajay C Donepudi; Gregory J Smith; Oladimeji Aladelokun; Yoojin Lee; Steven J Toro; Marisa Pfohl; Angela L Slitt; Li Wang; Ji-Young Lee; John D Schuetz; José E Manautou
Journal:  Toxicol Sci       Date:  2020-06-01       Impact factor: 4.849

7.  Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure.

Authors:  David S Umbaugh; Nga T Nguyen; Hartmut Jaeschke; Anup Ramachandran
Journal:  Toxicol Sci       Date:  2021-02-26       Impact factor: 4.849

8.  Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure.

Authors:  Pengfei Xu; Yue Xi; Pengcheng Wang; Zigmund Luka; Meishu Xu; Hung-Chun Tung; Jingyuan Wang; Songrong Ren; Dechun Feng; Bin Gao; Aatur D Singhi; Satdarshan P Monga; John D York; Xiaochao Ma; Zhiying Huang; Wen Xie
Journal:  Gastroenterology       Date:  2021-12-23       Impact factor: 22.682

9.  Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis.

Authors:  Kim H H Liss; Shelby E Ek; Andrew J Lutkewitte; Terri A Pietka; Mai He; Priya Skaria; Eric Tycksen; Daniel Ferguson; Valerie Blanc; Mark J Graham; Angela M Hall; Mitchell R McGill; Kyle S McCommis; Brian N Finck
Journal:  Liver Transpl       Date:  2020-10-22       Impact factor: 5.799

Review 10.  Biomarkers of drug-induced liver injury: a mechanistic perspective through acetaminophen hepatotoxicity.

Authors:  David S Umbaugh; Hartmut Jaeschke
Journal:  Expert Rev Gastroenterol Hepatol       Date:  2020-12-09       Impact factor: 3.869
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