Timothy Feeney1, Manuel Castillo-Angeles2, John W Scott2, Stephanie L Nitzschke2, Ali Salim2, Adil H Haider2, Joaquim M Havens3. 1. Harvard TH Chan School of Public Health, Boston, MA, USA; Brigham and Women's Hospital, Department of Surgery, Boston, MA, USA. 2. Brigham and Women's Hospital, Department of Surgery, Boston, MA, USA; Brigham and Women's Hospital Center for Surgery and Public Health, Boston, MA, USA. 3. Brigham and Women's Hospital, Department of Surgery, Boston, MA, USA; Brigham and Women's Hospital Center for Surgery and Public Health, Boston, MA, USA. Electronic address: jhavens@bwh.harvard.edu.
Abstract
BACKGROUND: Emergency general surgery (EGS) is an independent risk factor for morbidity and mortality, and seven procedures account for 80% of the National burden of operative EGS. We aimed to characterize the excess morbidity and mortality attributable to these procedures based on the level of procedural risk. METHODS: Retrospective analysis of the ACS National Surgical Quality Improvement Project (ACS-NSQIP) database. (2005-2014). Seven EGS procedures were stratified as high risk and low risk. Primary outcomes were overall mortality, overall morbidity, major morbidity. Multivariable logistic regression was performed. RESULTS: There were 619,174 patients identified. Comparing EGS to non-EGS in high-risk cases the OR for overall mortality was 1.39(1.33,1.45), overall morbidity 1.07 (0.98, 1.16), and major morbidity 1.15(1.03,1,27). In low-risk cases the OR for overall mortality was 1.03 (0.89, 1.19) overall morbidity 1.35 (1.23, 1.48), and major morbidity 2.18(1.90, 2.50). CONCLUSIONS: Using a Nationally representative clinical database we identified significant heterogeneity in the outcomes of EGS depending on procedural risk. Risk stratification and benchmarking strategies need to account for the inherent heterogeneity of EGS.
BACKGROUND: Emergency general surgery (EGS) is an independent risk factor for morbidity and mortality, and seven procedures account for 80% of the National burden of operative EGS. We aimed to characterize the excess morbidity and mortality attributable to these procedures based on the level of procedural risk. METHODS: Retrospective analysis of the ACS National Surgical Quality Improvement Project (ACS-NSQIP) database. (2005-2014). Seven EGS procedures were stratified as high risk and low risk. Primary outcomes were overall mortality, overall morbidity, major morbidity. Multivariable logistic regression was performed. RESULTS: There were 619,174 patients identified. Comparing EGS to non-EGS in high-risk cases the OR for overall mortality was 1.39(1.33,1.45), overall morbidity 1.07 (0.98, 1.16), and major morbidity 1.15(1.03,1,27). In low-risk cases the OR for overall mortality was 1.03 (0.89, 1.19) overall morbidity 1.35 (1.23, 1.48), and major morbidity 2.18(1.90, 2.50). CONCLUSIONS: Using a Nationally representative clinical database we identified significant heterogeneity in the outcomes of EGS depending on procedural risk. Risk stratification and benchmarking strategies need to account for the inherent heterogeneity of EGS.
Authors: Michael Arnold; Sharbel Elhage; Lynnette Schiffern; B Lauren Paton; Samuel W Ross; Brent D Matthews; Caroline E Reinke Journal: Surg Endosc Date: 2019-08-06 Impact factor: 4.584
Authors: Carol J Peden; Geeta Aggarwal; Robert J Aitken; Iain D Anderson; Nicolai Bang Foss; Zara Cooper; Jugdeep K Dhesi; W Brenton French; Michael C Grant; Folke Hammarqvist; Sarah P Hare; Joaquim M Havens; Daniel N Holena; Martin Hübner; Jeniffer S Kim; Nicholas P Lees; Olle Ljungqvist; Dileep N Lobo; Shahin Mohseni; Carlos A Ordoñez; Nial Quiney; Richard D Urman; Elizabeth Wick; Christopher L Wu; Tonia Young-Fadok; Michael Scott Journal: World J Surg Date: 2021-03-06 Impact factor: 3.352